FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Usp51
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General Information
Symbol
Dmel\Usp51
Species
D. melanogaster
Name
FlyBase ID
FBal0303912
Feature type
allele
Associated gene
Dmel\Usp5
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Kovacs et al., 2015)
Progenitor genotype
P{EPgy2}Usp5EY20760
(Kovacs et al., 2015)
Cytology
Description

Imprecise excision of P{EPgy2}Usp5EY20760 has resulted in a 275bp deletion which eliminates the catalytic histidine box and UBA2 domain coding sequence of Usp5.

(Kovacs et al., 2015)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3L:3,145,538..3,145,812 [-]
Comment:

Inferred boundaries of a 275bp deletion resulting from the imprecise excision of P{EPgy2}Usp5EY20760, which removes a region at the 3' end of Usp5 which contains the catalytic histidine box and UBA2 domain coding sequence.

(Kovacs et al., 2015)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Usp51 heterozygotes X-ray-irradiated as third instar larvae do not show changes in pupation or eclosion compared to controls, but adults show wing and eye abnormalities.

      (Páhi et al., 2022)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescued by

      Usp51 is partially rescued by Scer\GAL4da.PU/Usp5UAS.GFP

      (Kovacs et al., 2015)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      CG120821
      (Kovacs et al., 2015)
      DmUsp51
      (Kovacs et al., 2015)
      Usp51
      (Kovacs et al., 2015)
      usp51
      (Páhi et al., 2022)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)