FlyBase Allele Report: Dmel\mir-137[UAS.cSb]

General Information

Symbol

Dmel\mir-137^UAS.cSb

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct b of Szuplewski

FlyBase ID

FBal0304036

Feature type

allele

Associated gene

Dmel\mir-137

Associated Insertion(s)

Carried in Construct

M{UAS-mir-137.Sb}

PBac{UAS-mir-137.S}

Also Known As

UAS-miR-137

Key Links

Transgenic product class

wild_type

(Szuplewski et al., 2012)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Szuplewski et al., 2012)

Mutagen

in vitro construct

(Szuplewski et al., 2012)

Progenitor genotype

Carried in construct

M{UAS-mir-137.Sb}

PBac{UAS-mir-137.S}

Cytology

Description

UAS regulatory sequences drive expression of a genomic fragment containing the mir-137 miRNA stem loop plus approximately 100bp upstream and downstream.

(Szuplewski et al., 2012)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

mir-137

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | larval stage | somatic clone, with Scer\GAL4^Act.PU

(Padma et al., 2025)

decreased occurrence of cell division | larval stage, with Scer\GAL4^ey.PH

(Padma et al., 2025)

decreased size | adult stage, with Scer\GAL4^ey.PH

(Padma et al., 2025)

decreased size | adult stage, with Scer\GAL4^eyg-22-2

(Padma et al., 2025)

decreased size | adult stage, with Scer\GAL4^mirr-DE

(Padma et al., 2025)

decreased size | adult stage, with Scer\GAL4^nub-AC-62

(Padma et al., 2025)

decreased size | larval stage, with Scer\GAL4^ey.PH

(Padma et al., 2025)

decreased size | larval stage, with Scer\GAL4^eyg-22-2

(Padma et al., 2025)

decreased size | larval stage, with Scer\GAL4^mirr-DE

(Padma et al., 2025)

decreased size | larval stage, with Scer\GAL4^nub-AC-62

(Padma et al., 2025)

increased cell death | larval stage, with Scer\GAL4^ey.PH

(Padma et al., 2025)

lethal - all die before end of larval stage, with Scer\GAL4^αTub84B.PL

(Padma et al., 2025)

Phenotype Manifest In

eye, with Scer\GAL4^ey.PH

(Padma et al., 2025)

eye, with Scer\GAL4^eyg-22-2

(Padma et al., 2025)

eye disc | larval stage, with Scer\GAL4^ey.PH

(Padma et al., 2025)

eye disc | larval stage, with Scer\GAL4^eyg-22-2

(Padma et al., 2025)

eye disc dorsal compartment | larval stage, with Scer\GAL4^mirr-DE

(Padma et al., 2025)

eye dorsal compartment, with Scer\GAL4^mirr-DE

(Padma et al., 2025)

eye photoreceptor precursor cell | larval stage | somatic clone, with Scer\GAL4^Act.PU

(Padma et al., 2025)

filamentous actin | larval stage, with Scer\GAL4^ey.PH

(Padma et al., 2025)

wing, with Scer\GAL4^nub-AC-62

(Padma et al., 2025)

wing pouch | larval stage, with Scer\GAL4^nub-AC-62

(Padma et al., 2025)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Scer\GAL4^ey.PH, mir-137^UAS.cSb has decreased size | adult stage phenotype, non-enhanceable by Myc^JF01761, Scer\GAL4^ey.PH

(Padma et al., 2025)

Suppressed by

Statement

Reference

Scer\GAL4^ey.PH, mir-137^UAS.cSb has decreased size | adult stage phenotype, suppressible by Myc^UAS.cZa, Scer\GAL4^ey.PH

(Padma et al., 2025)

Scer\GAL4^ey.PH, mir-137^UAS.cSb has decreased size | larval stage phenotype, suppressible by Myc^UAS.cZa, Scer\GAL4^ey.PH

(Padma et al., 2025)

Scer\GAL4^ey.PH, mir-137^UAS.cSb has increased cell death | larval stage phenotype, suppressible | partially by BacA\p35^UAS.cHa, Scer\GAL4^ey.PH

(Padma et al., 2025)

Scer\GAL4^ey.PH, mir-137^UAS.cSb has decreased size | adult stage phenotype, suppressible | partially by BacA\p35^UAS.cHa, Scer\GAL4^ey.PH

(Padma et al., 2025)

Scer\GAL4^ey.PH, mir-137^UAS.cSb has decreased size | larval stage phenotype, suppressible | partially by BacA\p35^UAS.cHa, Scer\GAL4^ey.PH

(Padma et al., 2025)

NOT suppressed by

Statement

Reference

Scer\GAL4^ey.PH, mir-137^UAS.cSb has decreased size | adult stage phenotype, non-suppressible by Atg8a[+]/Atg8a^EP362

(Padma et al., 2025)

Scer\GAL4^ey.PH, mir-137^UAS.cSb has decreased size | adult stage phenotype, non-suppressible by Myc^JF01761, Scer\GAL4^ey.PH

(Padma et al., 2025)

NOT Enhancer of

Statement

Reference

mir-137^UAS.cSb, Scer\GAL4^ey.PH is a non-enhancer of decreased size | adult stage phenotype of Myc^JF01761, Scer\GAL4^ey.PH

(Padma et al., 2025)

Suppressor of

Statement

Reference

mir-137^UAS.cSb, Scer\GAL4^ey.PH is a suppressor | partially of abnormal size | adult stage phenotype of Ras85D^V12.UAS, Scer\GAL4^ey.PH, scrib^RNAi.UAS

(Padma et al., 2025)

mir-137^UAS.cSb, Scer\GAL4^ey.PH is a suppressor of increased size | larval stage phenotype of Ras85D^V12.UAS, Scer\GAL4^ey.PH, scrib^RNAi.UAS

(Padma et al., 2025)

NOT Suppressor of

Statement

Reference

mir-137^UAS.cSb, Scer\GAL4^ey.PH is a non-suppressor of decreased size | adult stage phenotype of Myc^JF01761, Scer\GAL4^ey.PH

(Padma et al., 2025)

Other

Statement

Reference

Myc^JF01761, Scer\GAL4^ey.PH, mir-137^UAS.cSb has decreased size | larval stage phenotype

(Padma et al., 2025)

Scer\GAL4^sca.PU, mi^GD11624, mir-137^UAS.cSb has lethal phenotype

(Szuplewski et al., 2012)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Scer\GAL4^ey.PH, mir-137^UAS.cSb has eye phenotype, non-enhanceable by Myc^JF01761, Scer\GAL4^ey.PH

(Padma et al., 2025)

Suppressed by

Statement

Reference

Scer\GAL4^ey.PH, mir-137^UAS.cSb has eye phenotype, suppressible by Myc^UAS.cZa, Scer\GAL4^ey.PH

(Padma et al., 2025)

Scer\GAL4^ey.PH, mir-137^UAS.cSb has eye disc | larval stage phenotype, suppressible by Myc^UAS.cZa, Scer\GAL4^ey.PH

(Padma et al., 2025)

Scer\GAL4^ey.PH, mir-137^UAS.cSb has eye disc | larval stage phenotype, suppressible | partially by BacA\p35^UAS.cHa, Scer\GAL4^ey.PH

(Padma et al., 2025)

Scer\GAL4^ey.PH, mir-137^UAS.cSb has eye phenotype, suppressible | partially by BacA\p35^UAS.cHa, Scer\GAL4^ey.PH

(Padma et al., 2025)

NOT suppressed by

Statement

Reference

Scer\GAL4^ey.PH, mir-137^UAS.cSb has eye phenotype, non-suppressible by Atg8a[+]/Atg8a^EP362

(Padma et al., 2025)

Scer\GAL4^ey.PH, mir-137^UAS.cSb has eye phenotype, non-suppressible by Myc^JF01761, Scer\GAL4^ey.PH

(Padma et al., 2025)

NOT Enhancer of

Statement

Reference

mir-137^UAS.cSb, Scer\GAL4^ey.PH is a non-enhancer of eye phenotype of Myc^JF01761, Scer\GAL4^ey.PH

(Padma et al., 2025)

Suppressor of

Statement

Reference

mir-137^UAS.cSb, Scer\GAL4^ey.PH is a suppressor | partially of eye phenotype of Ras85D^V12.UAS, Scer\GAL4^ey.PH, scrib^RNAi.UAS

(Padma et al., 2025)

mir-137^UAS.cSb, Scer\GAL4^ey.PH is a suppressor of eye disc | larval stage phenotype of Ras85D^V12.UAS, Scer\GAL4^ey.PH, scrib^RNAi.UAS

(Padma et al., 2025)

NOT Suppressor of

Statement

Reference

mir-137^UAS.cSb, Scer\GAL4^ey.PH is a non-suppressor of eye phenotype of Myc^JF01761, Scer\GAL4^ey.PH

(Padma et al., 2025)

Other

Statement

Reference

Myc^JF01761, Scer\GAL4^ey.PH, mir-137^UAS.cSb has eye disc | larval stage phenotype

(Padma et al., 2025)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

59881

w^*; PBac{UAS-mir-137.S}VK00037/CyO

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

mir-137^Scer\UAS.cSb

mir-137^UAS.cSb

Name Synonyms

Saccharomyces cerevisiae UAS construct b of Szuplewski

Secondary FlyBase IDs

References (3)

Report Sections

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