FlyBase Allele Report: Scer\GAL4[mirr-DE]

Drives embryonic expression in the mesoderm and in a segmentally repeated pattern in germ band extended embryo. Drives larval expression in the dorsal compartments of the eye and antennal discs; in the presumptive nota, pleura, and pouch regions of the wing and haltere discs; drives little to no expression in leg discs.

(FlyBase Curators, 2017)

ScerGAL4^mirr-DE drives reporter expression in the dorsal compartments of the eye and antennal discs. It also drives expression in the presumptive nota, pleura, and pouch regions of the wing and haltere discs. Little if any expression is driven in the leg discs. In the embryo, expression is driven in pattern of mirr expression, and is observed in the mesoderm and in a segmentally repeated pattern in germ band extended embryos.

(Morrison and Halder, 2010)

Marker for

Reflects expression of

mirr

(Morrison and Halder, 2010)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell growth, with Pten^KK109278

(Nowak et al., 2013)

abnormal size | adult stage, with Hrb27C^GD6964

(Mach et al., 2018)

abnormal size | third instar larval stage, with Tao^GD8262

(Boggiano et al., 2011)

abnormal size | third instar larval stage, with Tao^KK108458

(Boggiano et al., 2011)

decreased occurrence of cell division | larval stage, with Inx3^RNAi.UAS.WIZ

(Richard et al., 2017)

decreased size | adult stage, with mir-137^UAS.cSb

(Padma et al., 2025)

decreased size | larval stage, with mir-137^UAS.cSb

(Padma et al., 2025)

hypoplasia, with aurB^GL00202

(Wang et al., 2015)

hypoplasia, with aurB^JF03107

(Wang et al., 2015)

hypoplasia, with Cdk1^GL00262

(Wang et al., 2015)

hypoplasia, with Cdk1^JF03004

(Wang et al., 2015)

increased cell death, with Ubr3^KK100920

(Huang et al., 2014)

visible, with eya^GD1441

(Morrison and Halder, 2010)

visible | adult stage, with Hrb27C^GD6964

(Mach et al., 2018)

visible | adult stage, with Spyo\Cas9^UAS.uM, mbt^HD_CFD00807

(Pütz et al., 2021)

Phenotype Manifest In

cone cell | P-stage, with Past1^UAS.B.GFP

(Dorot et al., 2017)

eye, with fl(2)d^GD11887

(Anderson et al., 2014)

eye, with Nepl15^GD6237

(Nfonsam et al., 2012)

eye, with Pten^KK109278

(Nowak et al., 2013)

eye, with Spyo\Cas9^UAS.uM, mbt^HD_CFD00807

(Pütz et al., 2021)

eye | dorsal, with eya^GD1441

(Morrison and Halder, 2010)

eye disc, with Ubr3^KK100920

(Huang et al., 2014)

eye disc | dorsal | third instar larval stage, with Tao^GD8262

(Boggiano et al., 2011)

eye disc | dorsal | third instar larval stage, with Tao^KK108458

(Boggiano et al., 2011)

eye disc | larval stage, with aurB^GL00202

(Wang et al., 2015)

eye disc | larval stage, with aurB^JF03107

(Wang et al., 2015)

eye disc | larval stage, with Cdk1^GL00262

(Wang et al., 2015)

eye disc | larval stage, with Cdk1^JF03004

(Wang et al., 2015)

eye disc dorsal compartment | larval stage, with Inx3^RNAi.UAS.WIZ

(Richard et al., 2017)

eye disc dorsal compartment | larval stage, with mir-137^UAS.cSb

(Padma et al., 2025)

eye dorsal compartment, with Hrb27C^GD6964

(Mach et al., 2018)

eye dorsal compartment, with mir-137^UAS.cSb

(Padma et al., 2025)

interommatidial cell | P-stage | increased number, with Past1^UAS.B.GFP

(Dorot et al., 2017)

ommatidium | P-stage, with Past1^UAS.B.GFP

(Dorot et al., 2017)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^mirr-DE, Ubr3^KK100920 has increased cell death phenotype, suppressible by BacA\p35^UAS.cHa, Scer\GAL4^mirr-DE

(Huang et al., 2014)

NOT suppressed by

Statement

Reference

Scer\GAL4^mirr-DE, Ubr3^KK100920 has increased cell death phenotype, non-suppressible by Diap1^UAS.cHa, Scer\GAL4^mirr-DE

(Huang et al., 2014)

Scer\GAL4^mirr-DE, Ubr3^KK100920 has increased cell death phenotype, non-suppressible by Ubr1^UAS.Tag:FLAG/Scer\GAL4^mirr-DE

(Huang et al., 2014)

Suppressor of

Statement

Reference

Dronc^HMS00758/Scer\GAL4^mirr-DE is a suppressor of increased cell death | larval stage phenotype of hid^GMR.PG

(Farrell et al., 2022)

Dronc^HMS00758/Scer\GAL4^mirr-DE is a suppressor | partially of decreased size | adult stage phenotype of hid^GMR.PG

(Farrell et al., 2022)

gig^GD1454/Scer\GAL4^mirr-DE is a suppressor of decreased occurrence of cell division | somatic clone | third instar larval stage phenotype of smo³

(Kim et al., 2017)

BacA\p35^UAS.cHa, Scer\GAL4^mirr-DE is a suppressor of increased cell death phenotype of Scer\GAL4^mirr-DE, Ubr3^KK100920

(Huang et al., 2014)

NOT Suppressor of

Statement

Reference

Scer\GAL4^mirr-DE/tsr^UAS.cNa is a non-suppressor of decreased size | adult stage phenotype of hid^GMR.PG

(Farrell et al., 2022)

Scer\GAL4^mirr-DE/tsr^UAS.cNa is a non-suppressor of increased cell death | larval stage phenotype of hid^GMR.PG

(Farrell et al., 2022)

Scer\GAL4^mirr-DE/LIMK1^HMS04455 is a non-suppressor of decreased size | adult stage phenotype of hid^GMR.PG

(Farrell et al., 2022)

Scer\GAL4^mirr-DE/LIMK1^HMS04455 is a non-suppressor of increased cell death | larval stage phenotype of hid^GMR.PG

(Farrell et al., 2022)

Diap1^UAS.cHa, Scer\GAL4^mirr-DE is a non-suppressor of increased cell death phenotype of Scer\GAL4^mirr-DE, Ubr3^KK100920

(Huang et al., 2014)

Ubr1^UAS.Tag:FLAG/Scer\GAL4^mirr-DE is a non-suppressor of increased cell death phenotype of Scer\GAL4^mirr-DE, Ubr3^KK100920

(Huang et al., 2014)

Phenotype Manifest In

Suppressor of

Statement

Reference

Dronc^HMS00758/Scer\GAL4^mirr-DE is a suppressor of eye disc | larval stage phenotype of hid^GMR.PG

(Farrell et al., 2022)

Dronc^HMS00758/Scer\GAL4^mirr-DE is a suppressor | partially of eye | adult stage phenotype of hid^GMR.PG

(Farrell et al., 2022)

gig^GD1454/Scer\GAL4^mirr-DE is a suppressor of eye disc | somatic clone | third instar larval stage phenotype of smo³

(Kim et al., 2017)

Scer\GAL4^mirr-DE/mir-ban^as.A.UAS is a suppressor | somatic clone of eye disc | somatic clone phenotype of yki^B5

(Morrison and Halder, 2010)

NOT Suppressor of

Statement

Reference

Scer\GAL4^mirr-DE/LIMK1^HMS04455 is a non-suppressor of eye disc | larval stage phenotype of hid^GMR.PG

(Farrell et al., 2022)

Scer\GAL4^mirr-DE/LIMK1^HMS04455 is a non-suppressor of eye | adult stage phenotype of hid^GMR.PG

(Farrell et al., 2022)

Scer\GAL4^mirr-DE/tsr^UAS.cNa is a non-suppressor of eye disc | larval stage phenotype of hid^GMR.PG

(Farrell et al., 2022)

Scer\GAL4^mirr-DE/tsr^UAS.cNa is a non-suppressor of eye | adult stage phenotype of hid^GMR.PG

(Farrell et al., 2022)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^mirr-DE/fl(2)d^UAS.cAa rescues fl(2)d^GD11887

(Anderson et al., 2014)

Comments

Images (0)

Mutant

Wild-type

Stocks (3)

Bloomington

78371

sd¹² P{neoFRT}19A/FM6; P{GawB}mirr^DE/TM6B, Tb¹

29650

y¹ w^*; wg^Sp-1/CyO; P{GawB}mirr^DE/TM6B, Tb⁺

600566

w^*; P{UAS-Dcr-2.D}2; P{GawB}mirr^DE, P{tubP-GAL80^ts}20/TM6C, Sb¹ Tb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Scer\GAL4^mirr-DE

Name Synonyms

Secondary FlyBase IDs

References (52)

Report Sections

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