FlyBase Allele Report: Dmel\LIMK1[HMS04455]

General Information

Symbol

Dmel\LIMK1^HMS04455

Species

D. melanogaster

Name

FlyBase ID

FBal0301015

Feature type

allele

Associated gene

Dmel\LIMK1

Associated Insertion(s)

Carried in Construct

P{TRiP.HMS04455}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMS04455}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMS04455

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female semi-sterile, with Scer\GAL4^{VP16.mat.αTub67C}

(Sopko et al., 2014)

Phenotype Manifest In

Detailed Description

Statement

Reference

Females heterozygous for LIMK1^HMS04455 and Scer\GAL4^{mat.αTub67C.T:Hsim\VP16} crossed to LIMK1^HMS04455 males results in: 75% hatching; non-maternal effect.

(Sopko et al., 2014)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

LIMK1^HMS04455, Scer\GAL4^ey.PU is a suppressor | partially of increased size | adult stage phenotype of BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa

(Farrell et al., 2022)

LIMK1^HMS04455, Scer\GAL4^ey.PU is a suppressor | partially of visible | adult stage phenotype of BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa

(Farrell et al., 2022)

LIMK1^HMS04455, Scer\GAL4^ey.PU is a suppressor of increased occurrence of cell division | larval stage phenotype of BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa

(Farrell et al., 2022)

LIMK1^HMS04455, Scer\GAL4^nub.PK is a suppressor of increased size | larval stage phenotype of BacA\p35^UAS.cUa, Scer\GAL4^nub.PK, hid^UAS.cUa

(Farrell et al., 2022)

NOT Suppressor of

Statement

Reference

Scer\GAL4^mirr-DE/LIMK1^HMS04455 is a non-suppressor of decreased size | adult stage phenotype of hid^GMR.PG

(Farrell et al., 2022)

Scer\GAL4^mirr-DE/LIMK1^HMS04455 is a non-suppressor of increased cell death | larval stage phenotype of hid^GMR.PG

(Farrell et al., 2022)

Other

Statement

Reference

LIMK1^HMS04455, Scer\GAL4^mirr-DE, hid^UAS.cUa has abnormal size | adult stage phenotype

(Farrell et al., 2022)

Phenotype Manifest In

Suppressor of

Statement

Reference

LIMK1^HMS04455, Scer\GAL4^nub.PK is a suppressor of wing pouch | larval stage phenotype of BacA\p35^UAS.cUa, Scer\GAL4^nub.PK, hid^UAS.cUa

(Farrell et al., 2022)

LIMK1^HMS04455, Scer\GAL4^nub.PK is a suppressor of filamentous actin | larval stage phenotype of BacA\p35^UAS.cUa, Scer\GAL4^nub.PK, hid^UAS.cUa

(Farrell et al., 2022)

LIMK1^HMS04455, Scer\GAL4^Act.PU is a suppressor of eye disc | somatic clone | larval stage phenotype of BacA\p35^UAS.cUa, Scer\GAL4^Act.PU, hid^UAS.cUa

(Farrell et al., 2022)

LIMK1^HMS04455, Scer\GAL4^Act.PU is a suppressor of filamentous actin | somatic clone | larval stage phenotype of BacA\p35^UAS.cUa, Scer\GAL4^Act.PU, hid^UAS.cUa

(Farrell et al., 2022)

LIMK1^HMS04455, Scer\GAL4^ey.PU is a suppressor | partially of adult head phenotype of BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa

(Farrell et al., 2022)

LIMK1^HMS04455, Scer\GAL4^ey.PU is a suppressor of eye disc | larval stage phenotype of BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa

(Farrell et al., 2022)

NOT Suppressor of

Statement

Reference

Scer\GAL4^mirr-DE/LIMK1^HMS04455 is a non-suppressor of eye disc | larval stage phenotype of hid^GMR.PG

(Farrell et al., 2022)

Scer\GAL4^mirr-DE/LIMK1^HMS04455 is a non-suppressor of eye | adult stage phenotype of hid^GMR.PG

(Farrell et al., 2022)

Other

Statement

Reference

LIMK1^HMS04455, Scer\GAL4^mirr-DE, hid^UAS.cUa has eye disc | larval stage phenotype

(Farrell et al., 2022)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

57012

y¹ sc^* v¹ sev²¹; P{TRiP.HMS04455}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

LIMK1^HMS04455

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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