Open Close
General Information
Symbol
Dmel\tsrUAS.cNa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Ng
FlyBase ID
FBal0177368
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-tsr WT
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of the entire tsr ORF.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of tsrScer\UAS.cNa (using tub-Gal80[ts] to limit the expression to the adult stage) under the control of Scer\GAL4elav.PU does not significantly alter 3 hr memory of adult flies in an aversive olfactory assay compared to controls.

Expression of tsrScer\UAS.cNa under the control of Scer\GAL4109(2)80 results in the formation of Act5CScer\UAS.T:Avic\GFP accumulations in neuronal dendrites, with occasional rod-like structures forming.

Overexpression of tsrScer\UAS.cNa in mushroom body neurons under the control of Scer\GAL4OK107 does not result in gross axon or cell proliferation defects.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhanced by
Statement
Reference
Suppressed by
Statement
Reference
Suppressor of
Statement
Reference

Scer\GAL4ey-OK107/tsrUAS.cNa is a suppressor of adult mushroom body & axon | somatic clone phenotype of ssh1-11

Scer\GAL4ey-OK107/tsrUAS.cNa is a suppressor of antennal lobe & axon | somatic clone phenotype of ssh1-11

Scer\GAL4ey-OK107/tsrUAS.cNa is a suppressor of optic lobe neuron & axon | somatic clone phenotype of ssh1-11

Additional Comments
Genetic Interactions
Statement
Reference

Expression of tsrScer\UAS.cNa under the control of Scer\GAL4NP7175 significantly suppresses the axon growth phenotype seen in the α/β mushroom body lobes of sickA384/sickΔ mutants.

Longer rod-like structures of Act5CScer\UAS.T:Avic\GFP accumulation are formed in the dendrites of animals expressing tsrScer\UAS.cNa under the control of Scer\GAL4109(2)80 when the animals are also homozygous for captK304.

No rod-like structures of Act5CScer\UAS.T:Avic\GFP accumulation are formed in the dendrites of animals expressing tsrScer\UAS.cNa under the control of Scer\GAL4109(2)80 is they are also co-expressing captScer\UAS.cBa.

The axon growth and guidance defects seen in homozygous ssh1-11 adult mushroom body clones (which are generated as neuroblast clones in newly hatched larvae) are almost completely suppressed by co-expression of tsrScer\UAS.cNa under the control of Scer\GAL4OK107. The axon growth defects seen in neuroblast clones of optic lobe and antennal lobe contralateral projection neurons are partially suppressed by co-expression of tsrScer\UAS.cNa under the control of Scer\GAL4OK107.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Expression of tsrScer\UAS.cNa under the control of Scer\GAL4OK107 fully rescues the cell proliferation defects seen in homozygous tsrN96A adult mushroom body clones (which are generated as neuroblast clones in newly hatched larvae). Expression of tsrScer\UAS.cNa under the control of Scer\GAL4OK107 effectively rescues the axon growth defects seen in single cell tsrN96A γ neuron clones in the mushroom body.

Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
tsrScer\UAS.cNa
tsrUAS.cNa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Ng
Secondary FlyBase IDs
    References (11)