FB2026_02 , released June 18, 2026
Allele: Dmel\Scm82-01
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General Information
Symbol
Dmel\Scm82-01
Species
D. melanogaster
Name
FlyBase ID
FBal0304410
Feature type
allele
Associated gene
Dmel\Scm
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Guo and Jin, 2015)
Progenitor genotype
Cytology
Description

Amino acid replacement: W65term.

(Guo, 2016.1.15)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:9,636,962..9,636,962 [-]
Nucleotide change:

G9636962A

Reported nucleotide change:

G?A

Amino acid change:

W65term | Scm-PA; W65term | Scm-PB

Reported amino acid change:

W65term

Comment:

TGG to TAG nonsense mutation at codon W65.

(Guo, 2016.1.15)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Eyes mosaic for Scm82-01 (generated using the FRT/ey-FLP system) are overgrown. Mutant cells are missing, whereas neighbouring wild type cells are overgrown. These mutant flies demonstrated heads almost completely covered by mosaic eyes; an extra antenna accompanying the epicranium is also observed in these mutants. Furthermore, some ommatidia vary in size and polarity, exemplified by a single ommatidium often being accompanied by several bristles; ommatidia in these mutants are also fused in certain instances or completely absent. Mutant cells undergo apoptosis.

      The cuticle secreted by epidermal cells neighboring Scm82-01 mutant clones displays an unusual texture. Furthermore, in neighboring clones on the notum, the apical surfaces of epidermal cells are clearly demarcated, making cell-cell boundaries visible between adjacent cells.

      (Guo and Jin, 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Scm82-01 is rescued by ScmTub.PG

      (Guo and Jin, 2015)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      82-01
      (Guo and Jin, 2015)
      Scm82-01
      Name Synonyms
      Secondary FlyBase IDs
        References (2)