FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ClkSV40.Tag:V5
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General Information
Symbol
Dmel\ClkSV40.Tag:V5
Species
D. melanogaster
Name
FlyBase ID
FBal0304771
Feature type
allele
Associated gene
Dmel\Clk
Associated Insertion(s)
Carried in Construct
P{Clk.V5.SV40}
Also Known As
ClkSV40
Key Links
Transgenic product class
wild_type
(Lerner et al., 2015)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Lerner et al., 2015)
Mutagen
in vitro construct
(Lerner et al., 2015)
Progenitor genotype
Carried in construct
P{Clk.V5.SV40}
Cytology
Description

A 14.5-kilobase construct that expresses a C-terminal Tag:V5-tagged Clk without post-transcriptional control. It includes all known Clk coding and regulatory sequences but also carries an SV40 3' UTR inserted immediately downstream the open reading frame.

(Lerner et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
Clk
Encoded product / tool
Clk
Tagged with
Tag:V5
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Shortened circadian period accompanied by a higher proportion of arrhythmic flies is observed in flies with one extra copy of ClkT:SV5\V5.WT in addition to the endogenous Clk. There is high variability among the tested insertion lines.

      The number of Pdf neurons vary between brains in flies carrying ClkSV40.T:SV5\V5. Unlike in wild-type, the two lobes of individual flies carrying the transgene often have different number of Pdf neurons. The variable number of Pdf neurons within brain hemispheres and between transgenic individuals is also observed in pupae.

      (Lerner et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ClkSV40.T:SV5\V5
      ClkSV40.Tag:V5
      Name Synonyms
      Secondary FlyBase IDs
        References (2)