FB2026_02 , released June 18, 2026
Allele: Dmel\apc1.4b
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General Information
Symbol
Dmel\apc1.4b
Species
D. melanogaster
Name
FlyBase ID
FBal0304937
Feature type
allele
Associated gene
Dmel\ap
Associated Insertion(s)
TI{TI}apc1.4b
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Bieli et al., 2015)
gene conversion
(Bieli et al., 2015)
Progenitor genotype
P{(-loxP)(-FRT)Flipper2}apMM
(Bieli et al., 2015)
Associated Insertion(s)
TI{TI}apc1.4b
Cytology
Description

A gene conversion template plasmid (pLAPGPRA) was used containing homology arms flanking the site of the P{(-loxP)(-FRT)Flipper2}apMM insertion, along with hsp70-GFP bracketed by a pair of inverted attP sites. The injection of pLAPGPRA in the presence of a transposase source leads to gene conversion.

(Bieli et al., 2015)
Allele components
Component
Use(s)
Also carries
attP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The wings of apc1.4b homozygotes appear wild-type.

      (Bieli et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      The rough eye phenotype of homozygous apc1.4b can be separated from the ap locus by meiotic recombination. The rough eye phenotype is not observed for apc1.4b mutants over apDG3.

      (Bieli et al., 2015)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      apc1.4b
      (Bieli et al., 2015)
      c1.4b
      (Bieli et al., 2015)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)