FlyBase Allele Report: Dmel\Col4a1[UAS.mRFP1]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Dmel\Col4a1^UAS.mRFP1

General Information

Symbol

Dmel\Col4a1^UAS.mRFP1

Species

D. melanogaster

Name

FlyBase ID

FBal0316154

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

P{UAS-Col4a1.RFP}

Also Known As

UAS-Cg25C.RFP

Key Links

Transgenic product class

(Zang et al., 2015)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

(Zang et al., 2015)

Mutagen

in vitro construct

(Zang et al., 2015)

Progenitor genotype

Carried in construct

P{UAS-Col4a1.RFP}

Cytology

Description

UAS regulatory sequences drive expression of Col4a1 that is tagged at the C-terminal end with mRFP1.

(Zang et al., 2015)

Allele components

Component

Use(s)

Regulatory region(s)

binary expression system - regulatory region

Encoded product / tool

Tagged with

red fluorescent protein

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates Alzheimer's disease 1

modeled by Hsap\APP^{Arctic.UAS.Tag:SS(nec)}

(Catterson et al., 2023)

modeled by Hsap\APP^2xAPP.SP.UAS

(Catterson et al., 2023)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Col4a1^UAS.mRFP1, Scer\GAL4^{elav.Switch.PO} is a suppressor of short lived | RU486 conditional phenotype of Hsap\APP^2xAPP.SP.UAS, Scer\GAL4^{elav.Switch.PO}

(Catterson et al., 2023)

Col4a1^UAS.mRFP1, Scer\GAL4^GMR.PFa is a suppressor of visible | adult stage phenotype of Hsap\APP^2xAPP.SP.UAS, Scer\GAL4^GMR.PFa

(Catterson et al., 2023)

Col4a1^UAS.mRFP1, Scer\GAL4^GMR.PFa is a suppressor of decreased size | adult stage phenotype of Hsap\APP^2xAPP.SP.UAS, Scer\GAL4^GMR.PFa

(Catterson et al., 2023)

Col4a1^UAS.mRFP1, Scer\GAL4^{elav.Switch.PO} is a suppressor of short lived | RU486 conditional phenotype of Hsap\APP^{Arctic.UAS.Tag:SS(nec)}, Scer\GAL4^{elav.Switch.PO}

(Catterson et al., 2023)

Phenotype Manifest In

Suppressor of

Statement

Reference

Col4a1^UAS.mRFP1, Scer\GAL4^GMR.PFa is a suppressor of eye phenotype of Hsap\APP^2xAPP.SP.UAS, Scer\GAL4^GMR.PFa

(Catterson et al., 2023)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Cg25C^{Scer\UAS.T:Disc\RFP-mRFP}

Col4a1^{Scer\UAS.T:Disc\RFP-mRFP}

Col4a1^UAS.mRFP1

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections