FlyBase Allele Report: Dmel\grnd[extra.UAS]

General Information

Symbol

Dmel\grnd^extra.UAS

Species

D. melanogaster

Name

FlyBase ID

FBal0316441

Feature type

allele

Associated gene

Dmel\grnd

Associated Insertion(s)

Carried in Construct

M{UAS-grnd.extra}

Key Links

Transgenic product class

inframe_deletion

(Andersen et al., 2015)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

inframe_deletion

(Andersen et al., 2015)

Mutagen

in vitro construct

(Andersen et al., 2015)

Progenitor genotype

Carried in construct

M{UAS-grnd.extra}

Cytology

Description

UAS regulates expression of the extracellular domain of grnd, obtained from clone RE28509.

(Andersen et al., 2015)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

grnd

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates high grade glioma

modeled by Pi3K92E^{UAS.Tag:MYC,Tag:PM(hKRAS)}, btl::Egfr^λ.UAS

(Portela et al., 2019)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

The expression of grnd^extra.UAS under the control of Scer\GAL4^hh-Gal4 does not lead to any obvious phenotype in the wing disc, as compared to controls.

(de Vreede et al., 2018)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Scer\GAL4^Act.PU/grnd^extra.UAS is an enhancer of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-5^ccp-5

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is an enhancer of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-60^ccp-60

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is an enhancer of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-53^ccp-53

(Matsumoto et al., 2026)

NOT Enhancer of

Statement

Reference

Scer\GAL4^Act.PU/grnd^extra.UAS is a non-enhancer of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-37^ccp-37

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a non-enhancer of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-38^ccp-38

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a non-enhancer of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-41^ccp-41

(Matsumoto et al., 2026)

Suppressor of

Statement

Reference

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of Gli^SK2

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of Gli^ccp-56

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of Hel25E^ccp-8

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of nrv2^ccp-34

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of nrv2^k13315

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of bark^L200

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of bark^SK4

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of Elp3^ccp-2

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of Leng8^ccp-13

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of Leng8^ccp-44

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of wol^ccp-28

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-7^ccp-7

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-12^ccp-12

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-19^ccp-19

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-36^ccp-36

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-40^ccp-40

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-43^ccp-43

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-45^ccp-45

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-46^ccp-46

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-47^ccp-47

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-48^ccp-48

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-49^ccp-49

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-51^ccp-51

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-54^ccp-54

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-55^ccp-55

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-62^ccp-62

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-63^ccp-63

(Matsumoto et al., 2026)

grnd^extra.UAS, Scer\GAL4^repo is a suppressor of neoplasia | third instar larval stage phenotype of Pi3K92E^{UAS.Tag:MYC,Tag:PM(hKRAS)}, Scer\GAL4^repo, btl::Egfr^λ.UAS

(Portela et al., 2019)

grnd^extra.UAS, Scer\GAL4^repo is a suppressor of abnormal neuroanatomy | third instar larval stage phenotype of Pi3K92E^{UAS.Tag:MYC,Tag:PM(hKRAS)}, Scer\GAL4^repo, btl::Egfr^λ.UAS

(Portela et al., 2019)

grnd^extra.UAS/Scer\GAL4^hh-Gal4 is a suppressor | partially of neoplasia | larval stage phenotype of Alg3^tid2/Alg3^tid1

(de Vreede et al., 2018)

NOT Suppressor of

Statement

Reference

Scer\GAL4^Act.PU/grnd^extra.UAS is a non-suppressor of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-37^ccp-37

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a non-suppressor of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-38^ccp-38

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a non-suppressor of cell lethal | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-41^ccp-41

(Matsumoto et al., 2026)

Phenotype Manifest In

Enhancer of

Statement

Reference

Scer\GAL4^Act.PU/grnd^extra.UAS is an enhancer of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-5^ccp-5

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is an enhancer of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-60^ccp-60

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is an enhancer of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-53^ccp-53

(Matsumoto et al., 2026)

NOT Enhancer of

Statement

Reference

Scer\GAL4^Act.PU/grnd^extra.UAS is a non-enhancer of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-37^ccp-37

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a non-enhancer of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-38^ccp-38

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a non-enhancer of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-41^ccp-41

(Matsumoto et al., 2026)

Suppressor of

Statement

Reference

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of Gli^SK2

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of Gli^ccp-56

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of Hel25E^ccp-8

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of nrv2^ccp-34

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of nrv2^k13315

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of bark^L200

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of bark^SK4

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of Elp3^ccp-2

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of Leng8^ccp-13

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of Leng8^ccp-44

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of wol^ccp-28

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-7^ccp-7

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-12^ccp-12

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-19^ccp-19

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-36^ccp-36

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-40^ccp-40

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-43^ccp-43

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-45^ccp-45

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-46^ccp-46

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-47^ccp-47

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-48^ccp-48

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-49^ccp-49

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-51^ccp-51

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-54^ccp-54

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-55^ccp-55

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-62^ccp-62

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a suppressor of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-63^ccp-63

(Matsumoto et al., 2026)

grnd^extra.UAS, Scer\GAL4^repo is a suppressor of larval brain | third instar larval stage phenotype of Pi3K92E^{UAS.Tag:MYC,Tag:PM(hKRAS)}, Scer\GAL4^repo, btl::Egfr^λ.UAS

(Portela et al., 2019)

grnd^extra.UAS, Scer\GAL4^repo is a suppressor of larval glial cell | third instar larval stage phenotype of Pi3K92E^{UAS.Tag:MYC,Tag:PM(hKRAS)}, Scer\GAL4^repo, btl::Egfr^λ.UAS

(Portela et al., 2019)

grnd^extra.UAS, Scer\GAL4^repo is a suppressor of glial cell projection | third instar larval stage phenotype of Pi3K92E^{UAS.Tag:MYC,Tag:PM(hKRAS)}, Scer\GAL4^repo, btl::Egfr^λ.UAS

(Portela et al., 2019)

grnd^extra.UAS/Scer\GAL4^hh-Gal4 is a suppressor | partially of wing disc phenotype of Alg3^tid2/Alg3^tid1

(de Vreede et al., 2018)

grnd^extra.UAS/Scer\GAL4^GMR.PU is a suppressor of eye phenotype of Scer\GAL4^GMR.PU, egr^UAS.cMa

(Andersen et al., 2015)

NOT Suppressor of

Statement

Reference

Scer\GAL4^Act.PU/grnd^extra.UAS is a non-suppressor of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-37^ccp-37

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a non-suppressor of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-38^ccp-38

(Matsumoto et al., 2026)

Scer\GAL4^Act.PU/grnd^extra.UAS is a non-suppressor of eye disc | larval stage | somatic clone - tissue specific | conditional phenotype of ccp-41^ccp-41

(Matsumoto et al., 2026)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

grnd^{extra.Scer\UAS}

grnd^extra.UAS

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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