FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Toll-6Δcyto.UAS.GFP
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General Information
Symbol
Dmel\Toll-6Δcyto.UAS.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0316487
Feature type
allele
Associated gene
Dmel\Toll-6
Associated Insertion(s)
Carried in Construct
P{UAS-Toll-6.Δcyto.GFP}
Key Links
Transgenic product class
inframe_deletion
(Ward et al., 2015)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Ward et al., 2015)
Mutagen
in vitro construct
(Ward et al., 2015)
Progenitor genotype
Carried in construct
P{UAS-Toll-6.Δcyto.GFP}
Cytology
Description

UAS regulatory sequences drive expression of the extracellular and transmembrane domains of Toll-6 which are tagged at the C-terminal end with GFP.

(Ward et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Toll-6
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Toll-6Δcyto.Scer\UAS.T:Avic\GFP under the control of Scer\GAL4GMR71D09 causes lateral mistargeting of VM6 projection neuron dendrites.

      (Ward et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Toll-6Δcyto.UAS.GFP/Scer\GAL4Mz19 rescues Toll-6ex13

      (Ward et al., 2015)
      Comments

      Expression of Toll-6Δcyto.Scer\UAS.T:Avic\GFP under the control of Scer\GAL4Mz19 rescues the mistargeting phenotypes seen in the Scer\GAL4Mz19-positive projection neuron dendrites and VA1d olfactory receptor axons of Toll-6ex13 animals.

      (Ward et al., 2015)
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Toll-6Δcyto.Scer\UAS.T:Avic\GFP
      Toll-6Δcyto.UAS.GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (2)