FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Gpat421
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General Information
Symbol
Dmel\Gpat421
Species
D. melanogaster
Name
FlyBase ID
FBal0316583
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Progenitor genotype
Cytology
Description

Contains a 2bp deletion in the second exon of CG3209.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Comment:

A deletion of 2 bases in the second exon of Gpat4 leads to a frameshift.

Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

It takes CG320921 mutant larvae 8 days to pupate from 1st instar larvae, whereas for the control it takes 5 days. The CG320921 mutant larvae are smaller in size than controls. The rate and duration of the transition rate from first instar to second instar larvae is similar to controls, whereas the transitions from second to third and third to pupa are delayed.

CG320921/CG3209103 mutant flies do not show any detectable defects in survival or developmental rate.

The body size of CG320921 mutant adult flies shows little change from controls. No morphological defects are observed in the wing or eye.

The lipid droplets in the fat body of CG320921 mutant wandering third instar larvae and immature adults are of a similar area to controls. Triglyceride levels are also similar to controls.

CG320921 mutant larvae take longer to reach their peak food intake than controls: food intake during the second instar larval stage reduced compared with controls, similar for the third instar larval stage and increased during the wandering stage. Locomotion during the period is unaffected.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
CG320921
Gpat421
Name Synonyms
Secondary FlyBase IDs
    References (1)