FB2026_02 , released June 18, 2026
Allele: Dmel\PPO3SK3
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General Information
Symbol
Dmel\PPO3SK3
Species
D. melanogaster
Name
FlyBase ID
FBal0316884
Feature type
allele
Associated gene
Dmel\PPO3
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Dudzic et al., 2015)
Progenitor genotype
Cytology
Description

Frameshift mutation in the first exon.

(Dudzic et al., 2015)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2R:23,064,943..23,064,946 [+]
Comment:

4 bp deletion in the first exon.

(Dudzic et al., 2015)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutant flies have a normal lifespan compared to wild-type controls.

      Mutant larvae and adults show melanisation around the wound site after clean needle injury, as occurs in wild type.

      Mutant adults wild-type levels of survival after septic injury with Gram positive bacteria (Bacillus subtilis, Enterococcus faecalis or Staphylococcus aureus). Survival after natural infection with the fungus Beauveria bassiana is also wild type.

      (Dudzic et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      PPO3SK3
      (Dudzic et al., 2015)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)