FlyBase Allele Report: Dmel\cnn[EGFP]

General Information

Symbol

Dmel\cnn^EGFP

Species

D. melanogaster

Name

FlyBase ID

FBal0317019

Feature type

allele

Associated gene

Dmel\cnn

Associated Insertion(s)

Carried in Construct

PBac{cnn^eGFP}

Key Links

Transgenic product class

genomic_DNA

(Eisman et al., 2015)

wild_type

(Eisman et al., 2015)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

genomic_DNA

(Eisman et al., 2015)

wild_type

(Eisman et al., 2015)

Mutagen

in vitro construct

(Eisman et al., 2015)

Progenitor genotype

Carried in construct

PBac{cnn^eGFP}

Cytology

Description

Carries a genomic fragment of the cnn locus from (BAC CH322-189K22 from the CHORI BacPac library collection, https://bacpac.chori.org). Recombineering is used to fuse eGFP to the initiating methionine of exon 1A in the genomic BAC.

(Eisman et al., 2015)

Allele components

Component

Use(s)

Regulatory region(s)

cnn

Encoded product / tool

cnn

Tagged with

EGFP

green fluorescent protein

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

cnn^EGFP rescues cnn^HK21

(Eisman et al., 2015)

Comments

cnn^{T:Avic\GFP-EGFP} rescues the cnn^HK21 phenotype, with hatching rates of 51.5%, and restores fertility to both males and females.

(Eisman et al., 2015)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

cnn^EGFP

cnn^{T:Avic\GFP-EGFP}

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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