FB2026_02 , released June 18, 2026
Allele: Dmel\Ucp4ADL
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General Information
Symbol
Dmel\Ucp4ADL
Species
D. melanogaster
Name
FlyBase ID
FBal0318462
Feature type
allele
Associated gene
Dmel\Ucp4A
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Wu et al., 2014)
Progenitor genotype
P{EP}Ucp4AG1388
(Wu et al., 2014)
Cytology
Description

2.1kb deletion which removes almost the entire Ucp4A coding region including the translation start codon. Generated by imprecise excision of P{EP}Ucp4AG1388.

(Wu et al., 2014)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Paraquat or rotenone-induced lethality is enhanced in Ucp4ADL/Ucp4ADL flies compared to wild type.

      (Wu et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      Ucp4ADL/Ucp4ADL is an enhancer of increased mortality | chemical conditional phenotype of Pink1B9

      (Wu et al., 2014)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Pink1B9/Pink1B9 Ucp4ADL/Ucp4ADL double mutants have significantly shorter life spans in the presence of paraquat or rotenone compared to Pink1B9/Pink1B9 flies.

      (Wu et al., 2014)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Ucp4ADL
      ucp4ADL
      (Wu et al., 2014)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)