FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\LTV1E1
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General Information
Symbol
Dmel\LTV1E1
Species
D. melanogaster
Name
FlyBase ID
FBal0318466
Feature type
allele
Associated gene
Dmel\LTV1
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Kim et al., 2015)
Mutagen
P-element activity
(Kim et al., 2015)
Progenitor genotype
P{RS3}LTV1CB-6202-3
(Kim et al., 2015)
Cytology
Description

Imprecise excision of the progenitor, resulting in removal of the first half of the coding region of LTV1, including the start codon.

(Kim et al., 2015)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      LTV1E1 mutants arrest at the second larval stage and die ~6 days after egg hatching. Mutant clones in the fat body comprise smaller cells than controls.

      (Kim et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      LTV1E1 is rescued by Scer\GAL4da.PU/LTV1UAS.Tag:HA

      (Kim et al., 2015)

      LTV1E1 is rescued by LTV1UAS.Tag:HA/Scer\GAL4Cg.PA

      (Kim et al., 2015)
      Comments

      Scer\GAL4da.PU-mediated expression of LTV1Scer\UAS.T:Ivir\HA1 rescues the developmental arrest and lethality of LTV1E1 mutants, and Scer\GAL4Cg.PA-mediated expression of LTV1Scer\UAS.T:Ivir\HA1 rescues the decreased cell size phenotype seen in LTV1E1 clones in the fat body.

      (Kim et al., 2015)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      LTV1E1
      (Kim et al., 2015)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)