FB2026_02 , released June 18, 2026
Allele: Dmel\Rbfox1FF-AA
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General Information
Symbol
Dmel\Rbfox1FF-AA
Species
D. melanogaster
Name
FlyBase ID
FBal0319037
Feature type
allele
Associated gene
Dmel\Rbfox1
Associated Insertion(s)
Carried in Construct
PBac{Rbfox1.FF-AA}
Key Links
Transgenic product class
missense_variant
(Carreira-Rosario et al., 2016)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Carreira-Rosario et al., 2016)
Mutagen
in vitro construct
(Carreira-Rosario et al., 2016)
Progenitor genotype
Carried in construct
PBac{Rbfox1.FF-AA}
Cytology
Description

A genomic construct based on P[acman] clone CH321-94L16 containing full length Rbfox1 in which F158 and F160 within the RNA recognition motif are mutated to alanines to prevent RNA binding.

(Carreira-Rosario et al., 2016)
Allele components
Component
Use(s)
Regulatory region(s)
Rbfox1
Encoded product / tool
Rbfox1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      Rbfox1FF-AA fails to rescue Rbfox1e03440/Df(3L)ED4457

      (Carreira-Rosario et al., 2016)
      Comments

      Rbfox1+tCa (but not Rbfox1FF-AA) rescues the cystic tumor phenotype in Rbfox1e03440/Df(3L)ED4457 females.

      (Carreira-Rosario et al., 2016)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Rbfox1FF-AA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)