FlyBase Allele Report: Dmel\SCCRO3[J155]

General Information

Symbol

Dmel\SCCRO3^J155

Species

D. melanogaster

Name

FlyBase ID

FBal0319335

Feature type

allele

Associated gene

Dmel\SCCRO3

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

amorphic allele - molecular evidence

Mutagen

P-element activity

Nature of the Allele

Allele class

amorphic allele - molecular evidence

(Fu et al., 2016)

Mutagen

P-element activity

(Fu et al., 2016)

Progenitor genotype

P{GawB}NP0593

(Fu et al., 2016)

Cytology

Description

Deletion of the SCCRO3 promoter region and sequence encoding the N-terminal 204 amino acid residues.

(Fu et al., 2016)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal developmental rate | larval stage

(Fu et al., 2016)

decreased body size | third instar larval stage

(Fu et al., 2016)

female semi-fertile

(Fu et al., 2016)

short lived

(Fu et al., 2016)

viable

(Fu et al., 2016)

visible | third instar larval stage

(Fu et al., 2016)

Phenotype Manifest In

Detailed Description

Statement

Reference

SCCRO3^J155/SCCRO3^J155 flies show similar upward migration behavior to controls when knocked to the bottom of a glass jar. SCCRO3^J155/SCCRO3^J155 flies have a shorter lifespan than controls. The average number of F1 progeny per breeding pair (female mutant, wild type male) is significantly reduced in SCCRO3^J155/SCCRO3^J155 mutants compared to controls. SCCRO3^J155/SCCRO3^J155 mutants have significantly slower growth than controls during embryonic and larval stages (though they catch up by the time they hatch).

(Fu et al., 2016)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

SCCRO3^J155 has short lived phenotype, enhanceable by SCCRO^J34/SCCRO^J34

(Fu et al., 2016)

Enhancer of

Statement

Reference

SCCRO3^J155/SCCRO3^J155 is an enhancer of short lived phenotype of SCCRO^J34

(Fu et al., 2016)

Other

Statement

Reference

SCCRO3^J155, SCCRO^J34 has female semi-sterile phenotype

(Fu et al., 2016)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

SCCRO3^J155/SCCRO3^J155 SCCRO^J34/SCCRO^J34 double mutants have shorter lifespans and increased infertility compared to either single mutant (single mutants have shorter lifespans and decreased fertility compared to controls).

(Fu et al., 2016)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

J155

(Fu et al., 2016)

SCCRO3^J155

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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