FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\CarT1
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General Information
Symbol
Dmel\CarT1
Species
D. melanogaster
Name
FlyBase ID
FBal0319517
Feature type
allele
Associated gene
Dmel\CarT
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Xu et al., 2015)
Progenitor genotype
Cytology
Description

1112bp deletion that removes part of the CarT coding sequence.

(Xu et al., 2015)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2L:20,728,921..20,730,032 [-]
Comment:

A 1112 bp deletion removes part of the CarT coding sequence.

(Xu et al., 2015)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Electroretinogram recordings (ERGs) in response to light from CarT1/CarT1 mutants or mosaic flies with homozygous CarT1/CarT1 photoreceptors (but elsewhere heterozygous) do not show on or off transients and these mutants (along with CarT1/CarT2 flies) and mosaic flies show significant reductions in phototaxis.

      (Xu et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      CarT1 has eye phenotype, suppressible by Hsap\SLC22A2ninaE.PX

      (Xu et al., 2015)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Hsap\SLC22A2ninaE.PX restores on and off transients in ERGs and phototaxis in CarT1/CarT1 flies.

      (Xu et al., 2015)
      Complementation and Rescue Data
      Rescued by

      CarT1 is rescued by CarTmCherry

      (Xu et al., 2015)

      CarT1 is rescued by CarTninaE.PX

      (Xu et al., 2015)
      Not rescued by

      CarT1 is not rescued by CarTrdhB.PX

      (Xu et al., 2015)
      Comments

      CarTT:Disc\RFP-mCherry or CarTninaE.PX rescues on and off transients in ERGs and restores phototaxis similar to wild type in CarT1/CarT1 flies. CarTrdhB.PX fails to rescue on and off transients in ERGs in CarT1/CarT1 flies.

      (Xu et al., 2015)
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      CarT1
      carT1
      (Xu and Wang, 2019)
      cart1
      (Han et al., 2017, Xu et al., 2015)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)