FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Syx4UAS.A
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General Information
Symbol
Dmel\Syx4UAS.A
Species
D. melanogaster
Name
FlyBase ID
FBal0319661
Feature type
allele
Associated gene
Dmel\Syx4
Associated Insertion(s)
Carried in Construct
P{UAS-Syx4.A}
Key Links
Transgenic product class
wild_type
(Harris et al., 2016)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Harris et al., 2016)
Mutagen
in vitro construct
(Harris et al., 2016)
Progenitor genotype
Carried in construct
P{UAS-Syx4.A}
Cytology
Description

UAS regulatory sequences drive expression of the Syx4 A isoform.

(Harris et al., 2016)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Syx4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Syx4Scer\UAS.A driven by Scer\GAL4how-24B or Scer\GAL4elav.PLu does not significantly affect bouton number at the neuromuscular junction of third instar larvae, compared to controls.

      (Harris et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4how-24B/Syx4UAS.A rescues Syx473

      (Harris et al., 2016)
      Fails to rescue

      Syx4UAS.A/Scer\GAL4elav.PLu fails to rescue Syx473

      (Harris et al., 2016)
      Comments

      Expression of Syx4Scer\UAS.A driven by Scer\GAL4how-24B (but not Scer\GAL4elav.PLu) rescues bouton number at the neuromuscular junction of Syx473/Syx473 third instar larvae. Expression of Syx4Scer\UAS.A driven by Scer\GAL4how-24B also rescues active zone density at Syx473/Syx473 third instar larval NMJs.

      (Harris et al., 2016)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Syx4Scer\UAS.A
      Syx4UAS.A
      Name Synonyms
      Secondary FlyBase IDs
        References (1)