FlyBase Allele Report: Dmel\Tret1[UAS.PB]

General Information

Symbol

Dmel\Tret1^UAS.PB

Species

D. melanogaster

Name

FlyBase ID

FBal0319690

Feature type

allele

Associated gene

Dmel\Tret1

Associated Insertion(s)

Carried in Construct

P{UAS-Tret1.PB}

Key Links

Transgenic product class

wild_type

(Volkenhoff et al., 2015)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Volkenhoff et al., 2015)

Mutagen

in vitro construct

(Volkenhoff et al., 2015)

Progenitor genotype

Carried in construct

P{UAS-Tret1.PB}

Cytology

Description

UAS regulatory sequences drive expression of the Tret1-1-PB isoform.

(Volkenhoff et al., 2015)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Tret1

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Suppressor of

Statement

Reference

Scer\GAL4^da.PU/Tret1^UAS.PB is a non-suppressor of flightless phenotype of Tret1l^LL03974

(Volkenhoff et al., 2015)

Other

Statement

Reference

Df(2R)ΔTret, Scer\GAL4^da.PU, Tret1^UAS.PB has flightless phenotype

(Volkenhoff et al., 2015)

Df(2R)ΔTret, Scer\GAL4^da.PU, Scer\GAL80^repo.PL, Tret1^UAS.PB has lethal phenotype

(Volkenhoff et al., 2015)

Df(2R)ΔTret, Scer\GAL4^da.PU, Scer\GAL80^elav.PS, Tret1^UAS.PB has flightless phenotype

(Volkenhoff et al., 2015)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Expression of Tret1-1^Scer\UAS.PB driven by Scer\GAL4^da.PU shifts lethality associated with Df(2R)ΔTret/Df(2R)ΔTret mutants to adulthood; resulting flies are flightless. Expression of Tret1-1^Scer\UAS.PB driven by Scer\GAL4^da.PU does not rescue the flightless phenotype in Tret1-2^LL03974/Tret1-2^LL03974 flies. Expression of Tret1-1^Scer\UAS.PB driven by Scer\GAL4^da.PU in combination with Scer\GAL80^repo.PL does not rescue lethality in Df(2R)ΔTret/Df(2R)ΔTret mutants. Expression of Tret1-1^Scer\UAS.PB driven by Scer\GAL4^da.PU in combination with Scer\GAL80^elav.PS rescues lethality in Df(2R)ΔTret/Df(2R)ΔTret mutants; resulting flies are flightless.

(Volkenhoff et al., 2015)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Tret1-1^Scer\UAS.PB

Tret1-1^UAS.PB

Tret1^UAS.PB

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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