FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\obst-AΔ1
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General Information
Symbol
Dmel\obst-AΔ1
Species
D. melanogaster
Name
FlyBase ID
FBal0319752
Feature type
allele
Associated gene
Dmel\obst-A
Associated Insertion(s)
PBac{WHr}obst-AΔ1
Carried in Construct
Key Links
Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Tiklová et al., 2013)
Mutagen
FLPase
(Tiklová et al., 2013)
Progenitor genotype
PBac{WH}f02348
(Tiklová et al., 2013)
PBac{WH}f03687
(Tiklová et al., 2013)
Associated Insertion(s)
PBac{WHr}obst-AΔ1
Cytology
Description
Allele components
Component
Use(s)
Inserted element
PBac{WHr}
Regulatory region(s)
UAS
Also carries
FRT
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      obst-AΔ1/obst-AΔ1 mutants display larval lethality; larvae have a shortened body length as compared to heterozygote siblings or wild type; the dorsal trunk of late embryos shows a small but significant reduction in airway diameter, and some tortuosity, but no change in length; mutants show no difference in larval body width, and no obvious defects in patterning, dorsal closure or head involution, trachea do not display any obvious defects in epithelial integrity, no defect in tracheal gas-filling at the end of embryogenesis, as compared to wild type.

      (Tiklová et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      Statement
      Reference

      obst-AΔ1 has decreased body size | larval stage phenotype, enhanceable by Gaspd02290/Gaspd02290

      (Tiklová et al., 2013)
      Enhancer of
      Statement
      Reference

      obst-AΔ1/obst-AΔ1 is an enhancer of decreased body size | larval stage phenotype of Gaspd02290

      (Tiklová et al., 2013)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      obst-AΔ1/obst-AΔ1, Gaspd02290/Gaspd02290 double mutant larvae are shorter than either single mutant; the cuticles of first instar larvae appear severely bloated; the dorsal trunk of late embryos shows further reduction in airway diameter as compared with single mutants, but no change in length, and shows some tube tortuosity; trachea fail to become gas-filled at the end of embryogenesis and display some areas of local tube collapse and grossly irregular taenidial folds, but trachea do not display any obvious defects in epithelial integrity; larvae do not display any obvious defects in patterning, dorsal closure or head involution, as compared to wild type.

      (Tiklová et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      obst-AΔ1 is rescued by obst-AUAS.cTa

      (Tiklová et al., 2013)
      Comments

      Expression of obst-AScer\UAS.cTa under the control of Scer\GAL469B rescues the lethality of obst-AΔ1/obst-AΔ1 mutants.

      (Tiklová et al., 2013)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      obst-AΔ1
      (Tiklová et al., 2013)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)