FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Gaspd02290
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General Information
Symbol
Dmel\Gaspd02290
Species
D. melanogaster
Name
FlyBase ID
FBal0319754
Feature type
allele
Associated gene
Dmel\Gasp
Associated Insertion(s)
P{XP}Gaspd02290
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{XP}Gaspd02290
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    P{XP}
    Regulatory region(s)
    UAS
    Also carries
    FRT
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Gaspd02290/Gaspd02290 mutant larvae have shortened body length as compared to heterozygote siblings or wild type; trachea show some regions of local tube collapse; the dorsal trunk of late embryos shows a small but significant reduction in airway diameter, but no change in length; mutants show no difference in larval body width, no obvious defects in patterning, dorsal closure or head involution, trachea do not display any obvious defects in epithelial integrity, and do not show any defect in tracheal gas-filling at the end of embryogenesis, as compared to wild type.

        (Tiklová et al., 2013)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Enhanced by
        Statement
        Reference

        Gaspd02290 has decreased body size | larval stage phenotype, enhanceable by obst-AΔ1/obst-AΔ1

        (Tiklová et al., 2013)
        Enhancer of
        Statement
        Reference

        Gaspd02290/Gaspd02290 is an enhancer of decreased body size | larval stage phenotype of obst-AΔ1

        (Tiklová et al., 2013)
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        obst-AΔ1/obst-AΔ1, Gaspd02290/Gaspd02290 double mutant larvae are shorter than either single mutant; the cuticles of first instar larvae appear severely bloated; the dorsal trunk of late embryos shows further reduction in airway diameter as compared with single mutants, but no change in length, and shows some tube tortuosity; trachea fail to become gas-filled at the end of embryogenesis and display some areas of local tube collapse and grossly irregular taenidial folds, but trachea do not display any obvious defects in epithelial integrity; larvae do not display any obvious defects in patterning, dorsal closure or head involution, as compared to wild type.

        (Tiklová et al., 2013)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Gaspd02290
        Name Synonyms
        Secondary FlyBase IDs
          References (1)