FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Gyc76C3L043
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General Information
Symbol
Dmel\Gyc76C3L043
Species
D. melanogaster
Name
FlyBase ID
FBal0320357
Feature type
allele
Associated gene
Dmel\Gyc76C
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele

Mutagen
Nature of the Allele
Allele class

hypomorphic allele

(Schleede and Blair, 2015)
Mutagen
ethyl methanesulfonate
(Schleede and Blair, 2015)
Progenitor genotype
Cytology
Description

Amino acid replacement: L635H.

(Schleede and Blair, 2015)

Nucleotide substitution: A?T.

(Schleede and Blair, 2015)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3L:19,754,966..19,754,966 [-]
Nucleotide change:

T19754966A

Reported nucleotide change:

A?T

Amino acid change:

L635H | Gyc76C-PA; L635H | Gyc76C-PB; L635H | Gyc76C-PC; L635H | Gyc76C-PD

Reported amino acid change:

L635H

Comment:

Position of mutation on genomic sequence inferred by FlyBase curator from the reported nucleic acid and amino acid changes.

(Schleede and Blair, 2015)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Gyc76C3L043/Gyc76CKG03723ex33 transheterozygotes as well as Gyc76C3L043/Df(3L)Exel9061 mutants are lethal.

      Flies whose posterior wing compartment is largely composed of clones of Gyc76C3L043 homozygous mutant cells (induced in Minute/+ background to give them a growth advantage) show a complete loss of posterior cross vein.

      (Schleede and Blair, 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      Gyc76CKG03723ex33

      (Schleede and Blair, 2015)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Gyc76C3L043
      gyc76C3L043
      (Schleede and Blair, 2015)
      gyc76CL635H
      (Schleede and Blair, 2015)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)