FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\TmcUAS.cGa
Open Close
General Information
Symbol
Dmel\TmcUAS.cGa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Guo
FlyBase ID
FBal0321089
Feature type
allele
Associated gene
Dmel\Tmc
Associated Insertion(s)
Carried in Construct
P{UAS-Tmc.G}
Key Links
Transgenic product class
wild_type
(Guo et al., 2016)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Guo et al., 2016)
Mutagen
in vitro construct
(Guo et al., 2016)
Progenitor genotype
Carried in construct
P{UAS-Tmc.G}
Cytology
Description

UAS regulates expression of Tmc.

(Guo et al., 2016)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Tmc
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      TmcGal4 homozygote mutants expressing TmcScer\UAS.cGa under the control of Scer\GAL4Tmc-Gal4 do not display any defects in either the dendrite morphology of class I dopaminergic neurons or in axon projections of the Tmc-positive neurons in the ventral nerve cord.

      (Guo et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      TmcUAS.cGa rescues TmcGal4

      (Guo et al., 2016)
      Comments

      Expression of TmcScer\UAS.cGa under the control of Scer\GAL4Tmc-Gal4 rescues the larval locomotion defects (reduced crawling speed, increased head cast frequency, tendency to crawl backward) characteristic for TmcGal4 homozygotes.

      (Guo et al., 2016)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      TmcScer\UAS.cGa
      TmcUAS.cGa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Guo
      Secondary FlyBase IDs
        References (1)