FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Lmon\actAFP4CAAX.UAS.EGFP,Tag:M(hHRAS)
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General Information
Symbol
Lmon\actAFP4CAAX.UAS.EGFP,Tag:M(hHRAS)
Species
L. monocytogenes
Name
FlyBase ID
FBal0321121
Feature type
allele
Associated gene
Lmon\actA
Associated Insertion(s)
Carried in Construct
P{UAS-GFP-FP4CAAX}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Gates et al., 2007)
Progenitor genotype
Carried in construct
P{UAS-GFP-FP4CAAX}
Cytology
Description

UAS regulatory sequences drive expression of a portion of Lmon\actA which contains four "FP4" motifs (this is a binding motif for ena protein). A Tag:M(hHRAS) fragment is fused downstream of the Lmon\actA fragment. The Lmon\actA sequences are tagged at the N-terminal end with EGFP.

(Gates et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Lmon\actA
Tagged with
EGFP
Tag:M(hHRAS)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In

      filopodium & embryonic leading edge cell, with Scer\GAL4en-e16E

      (Gates et al., 2007)
      Detailed Description
      Statement
      Reference

      Embryos expressing Lmon\actAFP4CAAX.Scer\UAS.T:Avic\GFP-EGFP,T:Hsap\M-HRAS under the control of Scer\GAL4elav.PLu do not show an ISNb bypass phenotype.

      Leading edge cells in embryos expressing Lmon\actAFP4CAAX.Scer\UAS.T:Avic\GFP-EGFP,T:Hsap\M-HRAS under the control of Scer\GAL4en-e16E produce longer filopodia than wild type.

      (Gates et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Lmon\actAFP4CAAX.Scer\UAS.T:Avic\GFP-EGFP,T:Hsap\CAAX
      Lmon\actAFP4CAAX.Scer\UAS.T:Avic\GFP-EGFP,T:Hsap\M-HRAS
      Lmon\actAFP4CAAX.UAS.EGFP,Tag:M(hHRAS)
      Zzzz\actAFP4CAAX.Scer\UAS.T:Avic\GFP-EGFP,T:Hsap\CAAX
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0320507
      • FBal0218983
      References (2)