UASp regulatory sequences drive expression of mKO2 fused to the ubiquitination domain (amino acids 30-120) of the Homo sapiens CDT1 gene.
This construct is used as a fluorescent ubiquitination-based cell cycle indicator (Fucci) probe (see Sakaue-Sawano et al., 2008 - PMID:18267078).
This construct is used as a fluorescent ubiquitination-based cell cycle indicator (Fucci) probe (see Sakaue-Sawano et al., 2008 - PMID:18267078).