FB2026_02 , released June 18, 2026
Allele: Brsp\BphPnoGFP.iCasper.UAS
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General Information
Symbol
Brsp\BphPnoGFP.iCasper.UAS
Species
B. sp.
Name
FlyBase ID
FBal0321351
Feature type
allele
Associated gene
Brsp\BphP
Associated Insertion(s)
Carried in Construct
PBac{UAS-iCasper-noGFP-T2A-HO1}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Shu, 2015.10.20)
Progenitor genotype
Carried in construct
PBac{UAS-iCasper-noGFP-T2A-HO1}
Cytology
Description

UAS regulatory sequences drive expression of the 'iCasper-noGFP' sensor (an infra-red reporter of caspase activity). iCasper-noGFP is identical to the iCasper sensor (see FBrf0227896), except that the complementary split-GFP coding sequences that flank the infra-red fluorescent protein core of the sensor in iCasper have been replaced with leucine zipper dimerization motifs. The PBac{UAS-iCasper-noGFP-T2A-HO1} construct also produces the Hsap\HMOX1 protein, which is required to generate the biliverdin (BV) cofactor that the iCasper-noGFP infra-red fluorescent protein core requires to fluoresce.

(Shu, 2015.10.20)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Brsp\BphP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Brsp\BphPnoGFP.iCasper.Scer\UAS
      Brsp\BphPnoGFP.iCasper.UAS
      Zzzz\BrBphPnoGFP.iCasper.Scer\UAS
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0320737
      • FBal0317001
      References (4)