FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mei-W682-0949
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General Information
Symbol
Dmel\mei-W682-0949
Species
D. melanogaster
Name
FlyBase ID
FBal0321613
Feature type
allele
Associated gene
Dmel\mei-W68
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        mei-W682-0949/mei-W682-0949 mutant females show a reduction of meiotically-induced DNA double stranded breaks in the germaria, as compared to wild type.

        (Tran et al., 2016)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Suppressor of
        Statement
        Reference

        mei-W682-0949/mei-W682-0949 is a suppressor of abnormal meiotic cell cycle | female | temperature conditional phenotype of SMC6Δ35

        (Tran et al., 2016)
        Phenotype Manifest In
        Suppressor of
        Statement
        Reference

        mei-W682-0949/mei-W682-0949 is a suppressor of ovary phenotype of SMC6Δ35

        (Tran et al., 2016)

        mei-W682-0949/mei-W682-0949 is a suppressor of karyosome phenotype of SMC6Δ35

        (Tran et al., 2016)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        mei-W682-0949/mei-W682-0949, jnjΔ35/jnjΔ35 double mutants exhibit suppression of pachytene arrest and the delay in karyosome dynamics, as compared to jnjΔ35/jnjΔ35 single mutants.

        (Tran et al., 2016)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        mei-W682-0949
        mei-w682-0949
        (Tran et al., 2016)
        Name Synonyms
        Secondary FlyBase IDs
          References (1)