FB2026_02 , released June 18, 2026
Allele: Dmel\slp1UAS.cUa
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General Information
Symbol
Dmel\slp1UAS.cUa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Unknown
FlyBase ID
FBal0321735
Feature type
allele
Associated gene
Dmel\slp1
Associated Insertion(s)
Carried in Construct
P{UAS-slp1.U}
Also Known As
UAS-slp1
Key Links
Transgenic product class
wild_type
(FlyBase Curators, 2025-)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(FlyBase Curators, 2025-)
Mutagen
in vitro construct
(FlyBase Curators, 2025-)
Progenitor genotype
Carried in construct
P{UAS-slp1.U}
Cytology
Description

UAS regulatory sequences drive expression of slp1.

(FlyBase Curators, 2025-)

FlyBase curator comment: this entry represents a transgenic construct where the particular construct used cannot be determined.

(FlyBase Curators, 2025-)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
slp1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  Rett syndrome
      modeled by Hsap\MECP2R294X.UAS
      (Williams et al., 2016)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Expression of Hsap\MECP2R294X.Scer\UAS under the control of Scer\GAL4futsch-C380 (and Scer\GAL80ChAT.3.3P for adult flight assays) leads to apoptosis of motoneurons 5 in the pupal ventral nerve cord and inability of the adult flies to initiate flight; both these phenotypes can be partially rescued by co-expression of slp1Scer\UAS.cUa.

      (Williams et al., 2016)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      slp1Scer\UAS.cUa
      slp1UAS.cUa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Unknown
      Secondary FlyBase IDs
        References (5)