FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\domA.Tag:TY1,sfGFP,Tag:FLAG
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General Information
Symbol
Dmel\domA.Tag:TY1,sfGFP,Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0322590
Feature type
allele
Associated gene
Dmel\dom
Associated Insertion(s)
Carried in Construct
P{dom-A-GFP}
Key Links
Transgenic product class
genomic_DNA
(Börner and Becker, 2016)
wild_type
(Börner and Becker, 2016)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Börner and Becker, 2016)
wild_type
(Börner and Becker, 2016)
Mutagen
in vitro construct
(Börner and Becker, 2016)
Progenitor genotype
Carried in construct
P{dom-A-GFP}
Cytology
Description

Genomic fragment (derived from fosmid library clone pflyfos016675) encompassing the dom gene. The dom A isoform is tagged at the C-terminal end with a 2xTY1-sGFP-3xFLAG tag (isoform A corresponds to the protein encoded by the DOM-RA transcript, FlyBase release FB2016_03).

(Börner and Becker, 2016)
Allele components
Component
Use(s)
Regulatory region(s)
dom
Encoded product / tool
dom
Tagged with
sfGFP
Tag:FLAG
Tag:TY1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter or direct label
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      oogenesis & adult stage | female
      female germline cell
      (Börner and Becker, 2016)
      female germline stem cell
      (Börner and Becker, 2016)
      somatic cell of ovariole
      (Börner and Becker, 2016)
      follicle cell
      (Börner and Becker, 2016)
      oocyte
      (Börner and Becker, 2016)
      nurse cell
      (Börner and Becker, 2016)
      adult stage | female & oogenesis
      cystoblast
      (Börner and Becker, 2016)
      follicle stem cell
      (Börner and Becker, 2016)
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      domA.Tag:TY1,sfGFP,Tag:FLAG/Scer\GAL4VP16.mat.αTub67C rescues domHMS02208

      (Ibarra-Morales et al., 2021)
      Partially rescues

      domA.Tag:TY1,sfGFP,Tag:FLAG partially rescues domk08108

      (Börner and Becker, 2016)

      domA.Tag:TY1,sfGFP,Tag:FLAG partially rescues dom9

      (Börner and Becker, 2016)
      Comments

      Expression of domA.T:Scer\TY1,T:Avic\GFP-SF,T:Zzzz\FLAG partially rescues the pupal lethality of dom9/dom9 mutants, and surviving females do not exhibit a significant decrease in fertility.

      Expression of domA.T:Scer\TY1,T:Avic\GFP-SF,T:Zzzz\FLAG partially rescues the pupal lethality and larval lymph gland necrosis seen in domk08108/domk08108 mutants.

      (Börner and Becker, 2016)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      domA.T:Scer\TY1,T:Avic\GFP-SF,T:Zzzz\FLAG
      domA.Tag:TY1,sfGFP,Tag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (2)