FB2026_02 , released June 18, 2026
Allele: Dmel\sonaE475A.UAS
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General Information
Symbol
Dmel\sonaE475A.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0322729
Feature type
allele
Associated gene
Dmel\sona
Associated Insertion(s)
Carried in Construct
P{UAS-sona.E475A}
Key Links
Transgenic product class
missense_variant
(Kim et al., 2016)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Kim et al., 2016)
Mutagen
in vitro construct
(Kim et al., 2016)
Progenitor genotype
Carried in construct
P{UAS-sona.E475A}
Cytology
Description

UASt regulates expression of sona cDNA containing an E475A substitution, generating a protease mutant form.

(Kim et al., 2016)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
sona
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of sonaE475A.Scer\UAS under the control of Scer\GAL4nub.PU results in neither lethality nor any developmental defects.

      (Kim et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Statement
      Reference

      Scer\GAL4dpp.PU/sonaE475A.UAS is a non-suppressor of visible | adult stage phenotype of Scer\GAL4dpp.PU, wlsGD2418

      (Kim et al., 2016)
      Phenotype Manifest In
      NOT Suppressor of
      Statement
      Reference

      Scer\GAL4dpp.PU/sonaE475A.UAS is a non-suppressor of wing blade phenotype of Scer\GAL4dpp.PU, wlsGD2418

      (Kim et al., 2016)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The notched wing phenotype observed in flies expressing wlsGD2418 under the control of Scer\GAL4dpp.PU is not suppressed by co-expression of sonaE475A.Scer\UAS.

      (Kim et al., 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      sonaE475A.Scer\UAS
      sonaE475A.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)