FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Mcm3+tBa
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General Information
Symbol
Dmel\Mcm3+tBa
Species
D. melanogaster
Name
FlyBase ID
FBal0322755
Feature type
allele
Associated gene
Dmel\Mcm3
Associated Insertion(s)
Carried in Construct
PBac{Mcm3.B}
Key Links
Transgenic product class
genomic_DNA
(Blumröder et al., 2016)
wild_type
(Blumröder et al., 2016)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Blumröder et al., 2016)
wild_type
(Blumröder et al., 2016)
Mutagen
in vitro construct
(Blumröder et al., 2016)
Progenitor genotype
Carried in construct
PBac{Mcm3.B}
Cytology
Description

Genomic fragment encompassing the complete Mcm3 transcription unit.

(Blumröder et al., 2016)
Allele components
Component
Use(s)
Regulatory region(s)
Mcm3
Encoded product / tool
Mcm3
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The premature loss of mushroom body neuroblasts observed in the brain of Mcm3smu mutant pupae is not suppressed by combination with single copy of Df(3L)H99 (and thus removing one copy of several pro-apoptotic factors).

      (Blumröder et al., 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Mcm3+tBa rescues Mcm3smu

      (Blumröder et al., 2016)
      Comments

      The adult brain mushroom body structural defects characteristic for Mcm3smu mutants as well as the increased average size of the larval brain neuroblasts are rescued by combination with a single copy of Mcm3+tBa.

      (Blumröder et al., 2016)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Mcm3+tBa
      Name Synonyms
      Secondary FlyBase IDs
        References (1)