FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\pHCl-2Δ
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General Information
Symbol
Dmel\pHCl-2Δ
Species
D. melanogaster
Name
FlyBase ID
FBal0322784
Feature type
allele
Associated gene
Dmel\pHCl-2
Associated Insertion(s)
PBac{RB5.WH5}pHCl-2Δ
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
FLPase
(Feingold et al., 2016)
Progenitor genotype
PBac{WH}f00507
(Feingold et al., 2016)
PBac{RB}pHCl-2e00225
(Feingold et al., 2016)
Associated Insertion(s)
PBac{RB5.WH5}pHCl-2Δ
Cytology
Description

Recombination between the progenitor insertions resulting in a deletion of 13,980 bp, predicted to remove all but the first 30 amino acids of the 527 amino acid protein encoded by pHCl-2.

(Feingold et al., 2016)
Allele components
Component
Use(s)
Inserted element
PBac{RB5.WH5}
Regulatory region(s)
UAS
Also carries
FRT
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3R:31,290,817..31,304,797 [-]
(Feingold et al., 2016)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The basal fluid secretion rate of Malpighian tubules from pHCl-2Δ/pHCl-2Δ as well as pHCl-2Δ/pHCl-2MB03564 adult females is comparable to wild-type, whereas the secretion rate in pHCl-2Δ/Df(3R)Exel6218 is significantly increased.

      (Feingold et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      pHCl-2Δ
      (Feingold et al., 2016)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)