FlyBase Allele Report: Dmel\Tnpo[GS11030]

General Information

Symbol

Dmel\Tnpo^GS11030

Species

D. melanogaster

Name

FlyBase ID

FBal0323245

Feature type

allele

Associated gene

Dmel\Tnpo

Associated Insertion(s)

P{GSV6}Tnpo^GS11030

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

P{GSV6}Tnpo^GS11030

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{GSV6}

misexpression element

Regulatory region(s)

UASt

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3L:6,193,121..6,193,121

(Goodman et al., 2021, Nakayama et al., 2014)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of intellectual developmental disorder with hypotonia, impaired speech, and dysmorphic facies

CEC

(Goodman et al., 2021)

CEA

(Goodman et al., 2021)

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased size | adult stage, with Scer\GAL4^ey.PH

(Goodman et al., 2021)

decreased size | adult stage, with Scer\GAL4^GMR.PF

(Goodman et al., 2021)

lethal - all die before end of pupal stage, with Scer\GAL4^da.G32

(Goodman et al., 2021)

visible | adult stage, with Scer\GAL4^ey.PH

(Goodman et al., 2021)

visible | adult stage, with Scer\GAL4^GMR.PF

(Goodman et al., 2021)

visible | adult stage, with Scer\GAL4^nub.PK

(Goodman et al., 2021)

Phenotype Manifest In

eye, with Scer\GAL4^ey.PH

(Goodman et al., 2021)

eye, with Scer\GAL4^GMR.PF

(Goodman et al., 2021)

wing, with Scer\GAL4^nub.PK

(Goodman et al., 2021)

Detailed Description

Statement

Reference

The expression of Tnpo^GS11030 under the control of Scer\GAL4^ey.PH or Scer\GAL4^GMR.PF induces small and rough eyes. Expression under the control of Scer\GAL4^nub.PK induces wing notches and wing blisters.

(Goodman et al., 2021)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Kyoto

205260

y¹ w^67c23; P{GSV6}Tnpo^GS11030/TM3, Sb¹ Ser¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

GS11030

(Nakayama et al., 2014)

Tnpo^GS11030

Trn^GS11030

dTnpo^GS11030

(Goodman et al., 2021)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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