FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Zzzz\poly-GA50.UAS.EGFP
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General Information
Symbol
Zzzz\poly-GA50.UAS.EGFP
Species
a. artificial
Name
FlyBase ID
FBal0323571
Feature type
allele
Associated gene
Zzzz\poly-GA
Associated Insertion(s)
Carried in Construct
P{UAS-GFP-polyGA.50}
Also Known As
UAS-GFP-GA50, GFP-(GA)50
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Freibaum et al., 2015)
Progenitor genotype
Carried in construct
P{UAS-GFP-polyGA.50}
Cytology
Description

UASt regulatory sequences are fused upstream of sequence encoding an AUG start codon, the EGFP coding sequence and 50 GlyAla dipeptide repeats (the codons used avoid generating the pathogenic GGGGCC combination).

(Freibaum et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Zzzz\poly-GA
Tagged with
EGFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Zzzz\poly-GA50.Scer\UAS.T:Avic\GFP-EGFP under the control of Scer\GAL4GMR.PU does not lead to any apparent degenerative eye phenotype, as compared to controls.

      (Freibaum et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expressing Zzzz\poly-GA50.UAS.EGFP under the control of Scer\GAL4GMR.PF does not induce pupal lethality or visible eyes defects in Atx2KI.GFP, Atx2KI.ΔmIDR-GFP or Atx2KI.ΔcIDR-GFP homozygotes at either 18[o]C or 22[o]C.

      (Bakthavachalu et al., 2018)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Zzzz\poly-GA50.Scer\UAS.T:Avic\GFP-EGFP
      Zzzz\poly-GA50.UAS.EGFP
      Name Synonyms
      Secondary FlyBase IDs
        References (4)