FlyBase Allele Report: Dmel\if[MI12214-TG4.2]

General Information

Symbol

Dmel\if^{MI12214-TG4.2}

Species

D. melanogaster

Name

FlyBase ID

FBal0323676

Feature type

allele

Associated gene

Dmel\if

Associated Insertion(s)

Mi{Trojan-GAL4.2}if^{MI12214-TG4.2}

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

phiC31 integrase

Nature of the Allele

Allele class

Mutagen

phiC31 integrase

(Gene Disruption Project members, 2016-)

Progenitor genotype

Mi{MIC}if^MI12214

(Gene Disruption Project members, 2016-)

Associated Insertion(s)

Mi{Trojan-GAL4.2}if^{MI12214-TG4.2}

Cytology

Description

The RMCE cassette of the Mi{MIC}if^MI12214 insertion has been replaced with a Trojan-GAL4 cassette. The insertion is in a coding intron of if and is predicted to gene trap the gene. (Note that if this gene has multiple transcripts, only those where the insertion is in a coding intron are predicted to be trapped).

(Gene Disruption Project members, 2016-)

Allele components

Component

Use(s)

Inserted element

Mi{Trojan-GAL4.2}

gene trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

X:16,777,490..16,777,490 [+]

(Marcogliese et al., 2022, Lee et al., 2018, Gene Disruption Project members, 2016-)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal

(Lee et al., 2018)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

if^{MI12214-TG4.2} is rescued by if^UAS.cUa/Scer\GAL4^{if-MI12214-TG4.2}

(Lee et al., 2018)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

66867

y¹ w^* Mi{Trojan-GAL4.2}if^{MI12214-TG4.2}/FM7c

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

if^{MI12214-TG4.2}

if^TG4

(Marcogliese et al., 2022)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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