FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ITPVSH330029
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General Information
Symbol
Dmel\ITPVSH330029
Species
D. melanogaster
Name
FlyBase ID
FBal0324421
Feature type
allele
Associated gene
Dmel\ITP
Associated Insertion(s)
Carried in Construct
P{VSH330029}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Meadows, 2017.1.11)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Meadows, 2017.1.11)
Mutagen
in vitro construct
(Meadows, 2017.1.11)
Progenitor genotype
Carried in construct
P{VSH330029}
Cytology
Description

UAS regulatory sequences drive expression of a short hairpin microRNA (shRNA).

(Meadows, 2017.1.11)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dsRNA-VSH330029
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of ITPVSH330029 under the control of Scer\GAL4da.Switch.PT in adults fed with RU486 leads to a decreased proportion of body fluids, water intake, propensity to start drinking and size of feces; reduced survival under osmotic stress or under desiccation (with normal and lower dose of RU486); and an increase in the volume of consumed food and defecation rate when compared to controls.

      Expression of ITPVSH330029 under the control of Scer\GAL4ImpL2.RA (in combination with tub-Gal80[ts] to restrict the expression to adult stages) leads to reduced survival under desiccation or under osmotic stress when compared to control adults.

      (Gáliková et al., 2018)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      330029
      (Meadows, 2017.1.11)
      ITPVSH330029
      Name Synonyms
      Secondary FlyBase IDs
        References (2)