FB2026_02 , released June 18, 2026
Allele: Dmel\Atg14d13
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General Information
Symbol
Dmel\Atg14d13
Species
D. melanogaster
Name
FlyBase ID
FBal0325098
Feature type
allele
Associated gene
Dmel\Atg14
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Hegedűs et al., 2016)
Progenitor genotype
Cytology
Description

790bp deletion that results in a frameshift after the first 5 codons of Atg14, followed by a premature stop at codon 20 of the new reading frame.

(Hegedűs et al., 2016)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      In 3h-starved third instar larvae, Atg14d13 clones in the fat body exhibit a chain-like redistribution of lysosomes.

      (Takáts et al., 2021)

      Somatic clones of Atg14d13 mutant fat body cells almost completely lack acidic autolysosomes (as detected by Lysotracker staining) as well as autophagic structures.

      (Hegedűs et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Atg14d13
      (Csizmadia et al., 2018, Hegedűs et al., 2016)
      Atg14[d13]
      (Takáts et al., 2021)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)