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General Information
Symbol
Dmel\fit81
Species
D. melanogaster
Name
FlyBase ID
FBal0325459
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

fit is replaced with a w marker.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Starved fit81 mutant flies do not show any defects in detecting protein food and display normal preference for tryptone-supplemented (as a source of amino-acids) sucrose food over a sucrose-only food as controls, adult flies of both sexes also show no significant differences in body weight protein or lipid content compared to controls. However, in fit81 mutant adult females pre-feeding with tryptone leads to significantly weaker suppression of feeding (on standard food) compared to controls (pre-feeding with tryptone does not have a strong suppressive effect on feeding in males, either wild-type of fit81 mutant), pre-feeding with standard fly food or sucrose exerts normal feeding suppression in both females and males.

In a two-choice assay between sucrose-only and tryptone-supplemented food on unstarved flies, the fit81 mutants display similar feeding choices as the wild-type controls but the female mutant flies fail to adjust their feeding choice after tryptone pre-feeding and their preference for protein food remains high.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Expression of fitScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4fit.PS restores the disrupted suppressive effect of tryptone pre-feeding on feeding (on standard food) in fit81 adult females.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
fit81
Name Synonyms
Secondary FlyBase IDs
    References (1)