FB2026_02 , released June 18, 2026
Allele: Dmel\eyaRB.enh2
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General Information
Symbol
Dmel\eyaRB.enh2
Species
D. melanogaster
Name
FlyBase ID
FBal0325583
Feature type
allele
Associated gene
Dmel\eya
Associated Insertion(s)
Carried in Construct
PBac{enh2-eya-RB}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Weasner et al., 2016)
Progenitor genotype
Carried in construct
PBac{enh2-eya-RB}
Cytology
Description

586bp fragment corresponding to -576 to +10 relative to the transcription start site of the eya-RB isoform is fused upstream of a minimal Hsp70 promoter followed by a cDNA encoding the eya-RB isoform (plus 3'UTR).

(Weasner et al., 2016)
Allele components
Component
Use(s)
Encoded product / tool
eya
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Statement
      Reference

      eyaRB.enh2 is a non-suppressor of visible | adult stage phenotype of eya1, eyaRB.enhE

      (Weasner et al., 2016)
      Phenotype Manifest In
      NOT Suppressor of
      Statement
      Reference

      eyaRB.enh2 is a non-suppressor of eye phenotype of eya1, eyaRB.enhE

      (Weasner et al., 2016)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The small eye phenotype characteristic for eya1 homozygotes carrying the eyaRB.enhE transgene, i.e. partial rescue of the eyeless phenotype of the eya1 mutants, is not improved further by combination with eyaRB.enh2.

      (Weasner et al., 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      eyaRB.enh2 fails to rescue eya1

      (Weasner et al., 2016)

      eyaRB.enh2 fails to rescue eya2

      (Weasner et al., 2016)
      Comments

      Expression of eyaRB.enh2 fails to rescue the no-eye phenotype of either the eya2 or the eya1 homozygote adults.

      (Weasner et al., 2016)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      eyaRB.enh2
      Name Synonyms
      Secondary FlyBase IDs
        References (1)