FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\gbb::scwscwPD.gbbLD+Glc.UAS.Tag:FLAG
Open Close
General Information
Symbol
Dmel\gbb::scwscwPD.gbbLD+Glc.UAS.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0325638
Feature type
allele
Associated gene
gbb::scw
Associated Insertion(s)
Carried in Construct
M{UAS-scwPD::gbbLD+Glc}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Tauscher et al., 2016)
Progenitor genotype
Carried in construct
M{UAS-scwPD::gbbLD+Glc}
Cytology
Description

UAS regulatory sequences drive expression of a chimeric protein comprised of the scw prodomain fused to the gbb ligand domain. The gbb ligand domain has been mutated (carries the amino acid replacement T358N) to introduce a second N-glycosylation motif in the fusion protein (this additional motif is in the corresponding position to the scw-specific N-glycosylation motif found in scw). The open reading frame is tagged with Tag:FLAG.

(Tauscher et al., 2016)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
gbb::scw
Tagged with
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The loss of posterior crossvein characteristic for gbb5I/gbb4 can be partially rescued by Scer\GAL4dpp.3KK-driven expression of gbb::scwscwPD.gbbLD+Glc.Scer\UAS.T:Zzzz\FLAG in the mutant background.

      (Tauscher et al., 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      gbb::scwscwPD.gbbLD+Glc.Scer\UAS.T:Zzzz\FLAG
      gbb::scwscwPD.gbbLD+Glc.UAS.Tag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (1)