egg²¹³⁸/Df(2R)Dll-MP and egg²¹³⁸/Df(2R)ED4065 transheterozygotes are semi-lethal, display a very low male:female ratio, and the rare males die within 2-3 days. egg²¹³⁸/Df(2R)Dll-MP and egg²¹³⁸/Df(2R)ED4065 transheterozygous adults exhibit shaky, uncoordinated movements and held-out wings that are incompletely expanded, as compared to controls; these locomotor and wing phenotypes are more pronounced in males than in females.

The generation of egg²¹³⁸-homozygous germline clone cysts, either in larvae or adults, leads to an apparently normal progression of oogenesis until arrest and apoptosis of stage 5 egg chambers, as compared to controls. Although initially present in the germarium at similar frequency as controls, clonal egg²¹³⁸ germline stem cells become progressively lost after clone induction; egg²¹³⁸ follicle stem cell clones are initially less frequent in the ovary as compared to control clones, and also become progressively lost after clone induction.