FB2026_02 , released June 18, 2026
Allele: Dmel\Trf2UAS.s
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General Information
Symbol
Dmel\Trf2UAS.s
Species
D. melanogaster
Name
FlyBase ID
FBal0325801
Feature type
allele
Associated gene
Dmel\Trf2
Associated Insertion(s)
Carried in Construct
P{UAS-Trf2.s}
Key Links
Transgenic product class
cDNA
(Fan et al., 2017)
wild_type
(Fan et al., 2017)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Fan et al., 2017)
wild_type
(Fan et al., 2017)
Mutagen
in vitro construct
(Fan et al., 2017)
Progenitor genotype
Carried in construct
P{UAS-Trf2.s}
Cytology
Description

UASt regulatory sequences drive expression of Trf2 short isoform (632aa) cDNA.

(Fan et al., 2017)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Trf2
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Ectopic expression of Trf2Scer\UAS.s under the control of Scer\GAL4ppl.PP (at 29[o]C) leads to significant decrease in the lipid droplet size in the fat body of wandering third instar larvae.

      (Fan et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Trf2UAS.s/Scer\GAL4ppl.PP rescues Trf2G0071

      (Fan et al., 2017)
      Comments

      The increased size of fat body lipid droplets characteristic for Trf2G0071 mutant wandering third instar larvae can be rescued by expression of Trf2Scer\UAS.s under the control of Scer\GAL4ppl.PP in the mutant background (which on its own leads to reduced lipid droplet size).

      (Fan et al., 2017)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Trf2Scer\UAS.s
      Trf2UAS.s
      trf2s
      (Fan et al., 2017)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)