FB2026_02 , released June 18, 2026
Allele: Dmel\Gr28bUAS.A.cDa
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General Information
Symbol
Dmel\Gr28bUAS.A.cDa
Species
D. melanogaster
Name
FlyBase ID
FBal0325882
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Progenitor genotype
Carried in construct
Cytology
Description

UAS regulatory sequences drive expression of Gr28b A-isoform cDNA (from proboscis, legs and larvae).

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The expression of Gr28bScer\UAS.A.cDa under the control of Scer\GAL4Gr89a.2 leads to the following electrophysiological response changes of labellar sensilla to bitter tastants, as compared to controls: I-a sensilla display a novel and a significantly increased response to Myricetin and (-)-lobeline HCl, respectively; I-b sensilla display significantly increased responses to Aristolochic acid and Berberine chloride; S-a sensilla display no significant changes to the aforementioned tastants; these labellar sensilla types display no significant electrophysiological response changes to Rotenone, N,N-Diethyl-m-toluamide, Escin, Gossypol, Theobromine, Caffeine, Umbelliferone, Theophylline, Cucurbitacin I hydrate, D-(+)-sucrose octaacetate, Azadirachtin, Strychnine nitrate salt, Coumarin, Saponin, Sparteine sulfate salt, Quinine, and Denatonium benzoate.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

The expression of Gr28aScer\UAS.cDa under the control of Scer\GAL4Gr89a.2 leads to Gr59cΔ homozygous labellar I-a sensilla displaying a significantly increased response to Aristolochic acid but no significant change in their novel electrophysiological responses to Caffeine, Umbelliferone and Theophylline.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Gr28bScer\UAS.A.cDa
Gr28bUAS.A.cDa
Name Synonyms
Secondary FlyBase IDs
    References (1)