FB2026_02 , released June 18, 2026
Allele: Dmel\AdukΔ3b
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General Information
Symbol
Dmel\AdukΔ3b
Species
D. melanogaster
Name
FlyBase ID
FBal0326152
Feature type
allele
Associated gene
Dmel\Aduk
Associated Insertion(s)
P{?EPgy2}AdukΔ3b
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Braden and Neufeld, 2016)
Progenitor genotype
P{EPgy2}AdukEY18321
(Braden and Neufeld, 2016)
Associated Insertion(s)
P{?EPgy2}AdukΔ3b
Cytology
Description

705bp deletion within Aduk, removing most of the conserved kinase domain (including the ATP-binding pocket) and resulting in a frameshift leading to a premature stop codon after 6 codons. Generated by imprecise excision of Aduk; a 6bp remnant of the inserted element remains immediately downstream of the deletion.

(Braden and Neufeld, 2016)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3R:9,333,877..9,334,582 [-]
Comment:

706 bp deletion resulting from the imprecise excision of P{EPgy2}AdukEY18321. 6 bases from the P element remain at the site of the excision.

(Braden and Neufeld, 2016)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      AdukΔ3b mutant clones in larval fat body do not show any ectopic autophagy under unstressed conditions nor do they display any defects in developmental autophagy occurring during the wandering third larval instar stage or in starvation-induced autophagy.

      AdukΔ3b homozygous adults show reduced survival rate compared to controls.

      (Braden and Neufeld, 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ADUKΔ3b
      (Braden and Neufeld, 2016)
      AdukΔ3b
      Name Synonyms
      Secondary FlyBase IDs
        References (1)