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General Information
Symbol
Dmel\AdukΔ3b
Species
D. melanogaster
Name
FlyBase ID
FBal0326152
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Comment:

706 bp deletion resulting from the imprecise excision of P{EPgy2}AdukEY18321. 6 bases from the P element remain at the site of the excision.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Cytology
Nature of the lesion
Statement
Reference

705bp deletion within Aduk, removing most of the conserved kinase domain (including the ATP-binding pocket) and resulting in a frameshift leading to a premature stop codon after 6 codons. Generated by imprecise excision of Aduk; a 6bp remnant of the inserted element remains immediately downstream of the deletion.

Insertion components
P{?EPgy2}AdukΔ3b
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

AdukΔ3b mutant clones in larval fat body do not show any ectopic autophagy under unstressed conditions nor do they display any defects in developmental autophagy occurring during the wandering third larval instar stage or in starvation-induced autophagy.

AdukΔ3b homozygous adults show reduced survival rate compared to controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
AdukΔ3b
Name Synonyms
Secondary FlyBase IDs
    References (1)