FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Uxs1
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General Information
Symbol
Dmel\Uxs1
Species
D. melanogaster
Name
FlyBase ID
FBal0326171
Feature type
allele
Associated gene
Dmel\Uxs
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Matsumoto et al., 2016)
Mutagen
P-element activity
(Matsumoto et al., 2016)
Progenitor genotype
P{EPgy2}UxsEY00136
(Matsumoto et al., 2016)
Cytology
Description

1201bp deletion that removes the putative initiation codon and more than half the coding region of Uxs (including the nucleotide-binding site). Generated by imprecise excision of P{EPgy2}UxsEY00136.

(Matsumoto et al., 2016)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3L:8,181,005..8,182,205 [+]
Comment:

1201 bp deletion in Uxs resulting from the imprecise excision of P{EPgy2}UxsEY00136.

(Matsumoto et al., 2016)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Uxs1/Df(3L)Exel6112 transheterozygotes are lethal - most individuals dye at the late pupal stage but pharate adults are occasionally found.

      Uxs1/Df(3L)Exel6112 pharate adults display some missing bristles on both the dorsal head capsule and the scutellum, and display a rough eye phenotype, as compared to controls.

      Uxs1/Df(3L)Exel6112 third instar larvae exhibit no obvious in the number of either sensory organ precursor cells or supraalar neurons in the wing discs, as compared to controls.

      (Matsumoto et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The third instar larval wing discs of Uxs1/+, O-fut1R245AKI/O-fut1R245AKI individuals, but not Uxs1/Uxs1, O-fut1R245AKI/O-fut1R245AKI individuals, raised at 25[o]C of temperature, exhibit increased numbers of both sensory organ precursor cells and supraalar neurons, as compared to controls.

      (Matsumoto et al., 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Uxs1
      (Matsumoto et al., 2016)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)