FB2026_02 , released June 18, 2026
Allele: Dmel\inPD
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General Information
Symbol
Dmel\inPD
Species
D. melanogaster
Name
FlyBase ID
FBal0326334
Feature type
allele
Associated gene
Dmel\in
Associated Insertion(s)
TI{TI}inPD
Carried in Construct
Key Links
Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Wang et al., 2017)
Mutagen
CRISPR/Cas9
(Wang et al., 2017)
gene targeting by homologous recombination
(Wang et al., 2017)
Progenitor genotype
Associated Insertion(s)
TI{TI}inPD
Cytology
Description

Precise deletion of the in gene. A single loxP site is also present.

(Wang et al., 2017)
Allele components
Component
Use(s)
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      inPD mutant adults display multiple hair cell phenotype and abnormal polarity of both wing hairs and abdominal bristles.

      (Wang et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      inPD has wing hair phenotype, enhanceable by Scer\GAL4ap.PU/fyUAS.Tag:FLAG,Tag:OLLAS

      (Wang et al., 2017)
      Suppressed by
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The multiple hair cell phenotype and abnormal polarity of wing hairs characteristic for inPD mutant flies are weakly but significantly suppressed by expression of frtzScer\UAS.WALIUM.T:Hsap\MYC and enhanced by expression of fyScer\UAS.T:Zzzz\FLAG,T:Zzzz\OLLAS under the control of Scer\GAL4ap.PU in the mutant background.

      Scer\GAL4Act.PU-driven expression of frtzScer\UAS.WALIUM.T:Hsap\MYC partially rescues the abdominal bristles polarity phenotype of inPD flies.

      (Wang et al., 2017)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      inPD
      (Wang et al., 2017)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)