The R50D07 enhancer fragment is fused upstream of the Drosophila synthetic core promoter (DSCP) followed by the GAL4(DBD)::Zip- hemidriver (component of the 'Split GAL4' system, contains the GAL4 DNA-binding domain). A Hsp70 transcriptional terminator is present.
In a split-GAL4 system, Scer\GAL4DBD.R50D07 drives expression in lobula columnar neuron LC10b, lobula columnar neuron LC10c and a subset of neurons in the thoracico-abdominal ganglion when combined with Hsap\RELAAD.R72C08.
Comments on Models/Modifiers Based on Experimental Evidence
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Phenotype Manifest In
Inhibition (using Ctet\tetXTNT-LC.UAS) of neurons targeted by the split-GAL4 pair of Scer\GAL4DBD.R50D07 and Hsap\RELAAD.R72C08 in adult males does not affect their ability to orient towards and remain close to a female, compared to controls; there is also no effect on following of females or wing extensions, compared to controls.